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Anti-FGF basic antibody (ab73976)

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Overview

Product name

Anti-FGF basic antibody
See all FGF basic products (27) ...

Description

Chicken polyclonal to FGF basic

Specificity

ab73976 reacts with human recombinant FGF basic. No reactivity with other human serum proteins.

Tested applications

WB, ELISAmore details

Cross reactivity

Reacts with

Human

Immunogen

Purified full length native FGF basic protein

Positive control

Human recombinant FGF basic.

Properties

Form

Liquid

Storage instructions

Store at +4°C.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: 0.9% Sodium chloride

Concentration

Concentration information loading...

Purity

IgY fraction

Purification notes

The IgY fraction is isolated by a two step PEG precipitation procedure followed by ammonium sulphate precipitation.

Clonality

Polyclonal

Isotype

IgY

Research areas

Developmental Biology >> Organogenesis >> Excretory system development >> Kidney development
Cancer >> Invasion/microenvironment >> Angiogenesis >> Angiogenic growth factors
Cancer >> Growth factors >> FGF
Stem Cells >> Neural Stem Cells >> Extracellular
Neuroscience >> Neurology process >> Neurogenesis
Signal Transduction >> Growth Factors/Hormones >> FGF
Cardiovascular >> Angiogenesis >> Growth Factors >> FGF >> FGF

Applications

Show applications key

Our Abpromise guarantee covers the use of ab73976 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    WB

     WB: 1/1000. Predicted mo...Read more →

    WB: 1/1000. Predicted molecular weight: 17 kDa.

  • ELISA

     ELISA: 1/1000.

    ELISA: 1/1000.

Target

Function

Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.

Tissue specificity

Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non-cancerous liver tissue.

Sequence similarities

Belongs to the heparin-binding growth factors family.

Post-translational
modifications

Phosphorylation at Tyr-215 regulates FGF2 unconventional secretion.
Several N-termini starting at positions 94, 125, 126, 132, 143 and 162 have been identified by direct sequencing.

Cellular localization

Secreted. Exported from cells by an endoplasmic reticulum (ER)/Golgi-independent mechanism. Unconventional secretion of FGF2 occurs by direct translocation across the plasma membrane.

Target information above from: UniProt accessionP09038 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

Alternative names

  • Basic fibroblast growth factor antibody
  • BFGF antibody
  • FGF 2 antibody
  • FGF B antibody
  • FGF-2 antibody
  • FGF2 antibody
  • FGF2 basic antibody
  • FGF2_HUMAN antibody
  • FGFB antibody
  • Fibroblast growth factor 2 (basic) antibody
  • Fibroblast growth factor 2 antibody
  • HBGF 2 antibody
  • HBGF-2 antibody
  • HBGF2 antibody
  • HBGH 2 antibody
  • HBGH2 antibody
  • Heparin binding growth factor 2 precursor antibody
  • Heparin-binding growth factor 2 antibody
  • Prostatropin antibody
see all

Database links

References for Anti-FGF basic antibody (ab73976)

ab73976 has not yet been referenced specifically in any publications.

Publishing research using ab73976? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"