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Overview

  • Product nameFGF19 proteinSee all FGF19 proteins and peptides ...
  • Protein descriptionRecombinant FGF19 fragment (Human) containing 195 amino acid residues.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesGreater than 95% by SDS-PAGE. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised:Centrifuge the vial prior to opening. Reconstitute in 5-10 mM Sodium Phosphate, pH 8.0 to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4oC for 1 week or -20oC for future use. Repeated freeze thaw cycles will result in some loss of activity.
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • Concentration information loading...
  • Sequence notesMRPLAFSDAG PHVHYGWGDP IRLRHLYTSG PHGLSSCFLR IRADGVVDCA RGQSAHSLLE IKAVALRTVA IKGVHSVRYL CMGADGKMQG LLQYSEEDCA FEEEIRPDGY NVYRSEKHRL PVSLSSAKQR QLYKNRGFLP LSHFLPMLPM VPEEPEDLRG HLESDMFSSP LETDSMDPFG LVTGLEAVRS PSFEK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab50132 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
    Functional Studies FuncS: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab85042.

    • Protein info

    • Alternative names
        FGF 19FGF-19FGF15
        FGF19FGF19_HUMANFibroblast growth factor 15Fibroblast growth factor 19
      see all
  • FunctionInvolved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB.
  • Tissue specificityExpressed in fetal brain, cartilage, retina, and adult gall bladder.
  • Sequence similaritiesBelongs to the heparin-binding growth factors family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession O95750 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for FGF19 protein (ab50132)

    ab50132 has not yet been referenced specifically in any publications.

    Publishing research using ab50132 ? Please let us know so that we can cite the reference in this datasheet

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