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Products:Cardiovascular >> Angiogenesis >> Growth Factors >> FGF >> FGF
Overview
Product name
FGF21 protein
See all FGF21 products (11) ...
Protein description
Recombinant full length FGF21 protein (Mouse) total 183 AA, calculated MW 20.1kDa
Expression host
E. coli
Properties
Purity
>95% by SDS-PAGE
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
Constituents: 20mM Sodium chloride, 20mM Tris, pH 7.5
Concentration
Concentration information loading...
Additional notes
Product is NOT sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.
Sequence notes
M AYPIPDSSP LLQFGGQVRQ RYLYTDDDQD TEAHLEIRED GTVVGAAH RS PESLLELKAL KPGVIQILGV KASRFLCQQP DGALYGSP HF DPEACSFREL LLEDGYNVYQ SEAHGLPLRL PQKDSPNQ DA TSWGPVRFLP MPGLLHEPQD QAGFLPPEPP DVGSSDPL SM VEPLQGRSPS YAS
Research areas
Cancer >> Growth factors >> FGF
Signal Transduction >> Growth Factors/Hormones >> FGF
Cardiovascular >> Angiogenesis >> Growth Factors >> FGF >> FGF
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SDS-PAGE - FGF21 protein (ab63277)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab63277 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 20 kDa.
ELISA: Use at an assay dependent dilution.
Protein info
Function
Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
Sequence similarities
Belongs to the heparin-binding growth factors family.
Cellular localization
Secreted.
Target information above from: UniProt accessionQ9NSA1
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
FGF21 protein images:
SDS-PAGE - FGF21 protein (ab63277)
LANES: 1. MW marker – 14, 21, 31, 45, 66, 97 kDa 2. reduced and heated sample, 5µg/lane 3. non-reduced and non-heated sample, 5µg/lane
References for FGF21 protein (ab63277)
ab63277 has not yet been referenced specifically in any publications.
Publishing research using ab63277? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"