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Product Name
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FGF4 protein
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Product type
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Proteins and Peptides
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Peptide
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Recombinant fragment, corresponding to amino acids 25/206 of Human FGF4 with sequence GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
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Tested applications
(see key)
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FuncS, SDS-PAGE
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Application notes
(see key)
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Recommended dilutions
FuncS: Use at an assay dependent dilution.
Note: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/mg.
SDS-PAGE: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Research areas
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Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Growth factors
Cancer >> Growth factors >> FGF
Signal Transduction >> Growth Factors/Hormones >> FGF
Cardiovascular >> Angiogenesis >> Growth Factors >> FGF >> FGF
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Relevance
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FGF4 is a heparin binding growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF4 signals through the FGFR 1c, 2c, 3c, and 4.
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Purity
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>95% by SDS-PAGE
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Purification notes
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Greater than 95% by SDS-PAGE.
Endotoxin level is less than 0.1 ng per µg (1EU/µg).
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Form
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Lyophilised
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Expression system
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E. coli
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Sequence
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GRGGAAAPTA PNGTLEAELE RRWESLVALS LARLPVAAQP KEAAVQSGAG DYLLGIKRLR RLYCNVGIGF HLQALPDGRI GGAHADTRDS LLELSPVERG VVSIFGVASR FFVAMSSKGK LYGSPFFTDE CTFKEILLPN NYNAYESYKY PGMFIALSKN GKTKKGNRVS PTMKVTHFLP RL
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this FGF4 protein is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to FGF4
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FGF4 protein - more information
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Customer reviews (feedback) regarding FGF4 protein |
Customer FAQs regarding FGF4 protein |
Protocols for FGF4 protein |
Price and availability of products related to FGF4 protein |
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Contact Abcam with a Technical Enquiry about FGF4 protein |
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