Overview
Product nameFGF5 protein (Active)See all FGF5 proteins and peptides ...
Protein descriptionRecombinant Human FGF-5, a 27.6 kDa protein consisting of 252 amino acid residues.
Expression hostE. coli
Properties
Purity> 95
% by SDS-PAGE
Purification notesEndotoxin level is less than 0.1 ng per µg (1EU/µg).
FormLyophilised:Centrifuge the vial prior to opening. Reconstitute in 1x PBS, pH 7.2 to a concentration of 0.5–1.0 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze thaw cycles will result in some loss of activity.
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
Concentration information loading...
Sequence notesMAWAHGEKRL APKGQPGPAA TDRNPIGSSS RQSSSSAMSS SSASSSPAAS LGSQGSGLEQ SSFQWSPSGR RTGSLYCRVG IGFHLQIYPD GKVNGSHEAN MLSVLEIFAV SQGIVGIRGV FSNKFLAMSK KGKLHASAKF TDDCKFRERF QENSYNTYAS AIHRTEKTGR EWYVALNKRG KAKRGCSPRV KPQHISTHFL PRFKQSEQPE LSFTVTVPEK KNPPSPIKSK IPLSAPRKNT NSVKYRLKFR FG
Research Areas
Applications
Our Abpromise guarantee covers the use of
ab50229
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Application
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Notes |
| SDS-PAGE |
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| Functional Studies |
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Application notesFuncS: Use at an assay dependent dilution. The ED50, determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is < 0.5 ng/ml, corresponding to a specific activity of > 2 x 106 units/mg.
SDS-PAGE: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Protein info
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Alternative names
FGF5_HUMANFibroblast growth factor 5HBGF 5HBGF-5heparin binding growth factor 5Heparin-binding growth factor 5Smag 82Smag-82
see all
FunctionFunctions as an inhibitor of hair elongation by promoting progression from anagen, the growth phase of the hair follicle, into catagen the apoptosis-induced regression phase.
Tissue specificityExpressed in neonatal brain.
Sequence similaritiesBelongs to the heparin-binding growth factors family.
Developmental stageCan transform NIH 3T3 cells.
Cellular localizationSecreted.
References for FGF5 protein (Active) (ab50229)
ab50229
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
