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Products:Tags & Cell Markers >> Subcellular Markers >> Organelles >> Centrosome
Overview
Product name
Anti-FGFR1 Oncogene Partner antibody
See all FGFR1 Oncogene Partner products (3) ...
Description
Rabbit polyclonal to FGFR1 Oncogene Partner
Specificity
ab53071 detects endogenous levels of total FGFR1 protein.
Tested applications
WB, IHC-P, ELISAmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
A synthetic peptide derived from human FGFR1.
Positive control
Human breast carcinoma tissue and HepG2 cell extracts.
Properties
Form
Liquid
Storage instructions
Store at -20°C. Stable for 12 months at -20°C
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
ab53071 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Growth factors >> FGF
Cell Biology >> Other Antibodies >> Other Antibodies
Tags & Cell Markers >> Subcellular Markers >> Organelles >> Centrosome
Applications
Show applications key
Our Abpromise guarantee covers the use of ab53071 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
IHC-P
ELISA
Application notes
ELISA: 1/10000.
IHC-P: 1/50 - 1/100. Antigen retrieval method: sodium citrate buffer (pH 6.0)
WB: 1/500 - 1/1000. Detects a band of approximately 92 kDa (predicted molecular weight: 92 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
FGFR1 Oncogene Partner is required for anchoring microtubules to the centrosomes. Ubiquitous; highly expressed in heart, liver, muscle, kidney, intestine, colon, adrenal gland, prostate, testis, and pancreas. A chromosomal aberration involving FGFR1OP may be a cause of stem cell myeloproliferative disorder (MPD). There are three named isoforms.
Cellular localization
Centrosome. Associated with gamma-tubulin.
Alternative names
- FGFR1OP antibody
- Fibroblast growth factor receptor 1 oncogene partner antibody
- FOP antibody
see all
Database links
- Entrez Gene: 11116 Human
- Entrez Gene: 75296 Mouse
- Entrez Gene: 365103 Rat
- Omim: 605392 Human
- SwissProt: O95684 Human
- SwissProt: Q66JX5 Mouse
- SwissProt: Q4V7C1 Rat
Anti-FGFR1 Oncogene Partner antibody images:
Western blot - FGFR1 antibody (ab53071)
All lanes : Anti-FGFR1 Oncogene Partner antibody (ab53071) at 1/500 dilution
Lane 1 : HepG2 cell extract
Lane 2 : HepG2 cell extract with immunising peptide
Predicted band size : 92 kDa
Observed band size : 92 kDa
Immunohistochemistry (Paraffin-embedded sections) - FGFR1 antibody (ab53071)
ab53071 at 1/50 dilution staining FGFR1 in human breast carcinoma by Immunohistochemistry, Paraffin embedded tissue, in the absence and presence of the immunising peptide.
References for Anti-FGFR1 Oncogene Partner antibody (ab53071)
ab53071 has not yet been referenced specifically in any publications.
Publishing research using ab53071? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"