FGFR4 protein (Fc Chimera) (ab83999)
Constituents: 10% Trehalose, 1% Human serum albumin
Our Abpromise guarantee covers the use of ab83999 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Molecular Mass: ab83999 migrates as a broad band between 55 and 65 kDa in SDS-PAGE due to post-translation modifications, in particular glycosylation. This compares with the unmodified protein which has a predicted molecular mass of 47.1 kDa.
pI: ab83999 separates into a number of isoforms with a pI between 5.9 and 7.6 in 2D PAGE due to post-translational modifications, in particular glycosylation. This compares with the unmodified protein which has a predicted pI of 8.19.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
- CD 334CD334CD334 antigen
- fc13h 10fc13h10Fgfr 4FGFR-4Fgfr4FGFR4_HUMANFibroblast growth factor receptor 4Hydroxyaryl protein kinaseJTK 2JTK2MGC20292Protein tyrosine kinaseTKFTyrosine kinase related to fibroblast growth factor receptorTyrosylprotein kinase
Contains 3 Ig-like C2-type (immunoglobulin-like) domains.
Contains 1 protein kinase domain.
Phosphorylated on tyrosine residue (By similarity). Phosphorylation requires the presence of a functional (phosphorylated) FGFR1 and not necessarily by means of FGFR heterodimerization.
FGFR4 protein (Fc Chimera) images
Densitometry of protein isoforms visualised by 2-DE.
The densitometry scan demonstrates the purified human cell expressed protein exists in multiple isoforms, which differ according to their level of post-translational modification.
The triangle indicates the theoretical MW and pI of the protein.
References for FGFR4 protein (Fc Chimera) (ab83999)
ab83999 has not yet been referenced specifically in any publications.