Overview
- Product nameAnti-FGR antibodySee all FGR primary antibodies ...
- DescriptionMouse monoclonal to FGR
- Tested applicationsWB, IHC-P more details
- Species reactivityReacts with: Human
- Immunogen
Recombinant fragment: MGCVFCKKLE PVATAKEDAG LEGDFRSYGA ADHYGPDPTK ARPASSFAHI PNYSNFSSQA INPGFLDSGT IRGVSGIGVT LFIALYDYEA , corresponding to amino acids 1-90 of Human FGR
Properties
- FormLiquid
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
- Storage bufferPreservative: None
PBS, pH 7.2 -
Concentration information loading... - PurityProtein G purified
- Clonality Monoclonal
- IsotypeIgG2a
- Light chain typekappa
- Research Areas
Applications
Our Abpromise guarantee covers the use of ab58228 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Notes |
|---|---|
| WB | |
| IHC-P |
IHC-P: Use at a concentration of 3 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
- RelevanceFgr is a member of the Src family of non-receptor tyrosine kinases. It is expressed in neutrophils, monocytes, macrophages and natural killer cells. Expression of Fgr is developmentally regulated and required in normal myelomonocytic differentiation in vivo. HL-60 cells induced to differentiate with retinoic acid express high levels of Fgr.
- Cellular localizationCell membrane; Lipid-anchor; Cytoplasmic side Probable. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection › ruffle membrane. Cytoplasm › cytosol. Cytoplasm › cytoskeleton. Mitochondrion inner membrane. Mitochondrion intermembrane space. Note: Detected in mitochondrial intermembrane space and at inner membranes. Colocalizes with actin fibers at membrane ruffles. Detected at plasma membrane lipid rafts.
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Database links
- Entrez Gene: 2268 Human
- Entrez Gene: 2268 Human
- Entrez Gene: 2268 Human
- NCBI: 4885235 Human
- Omim: 164940 Human
- SwissProt: P09769 Human
- SwissProt: P09769 Human
- SwissProt: P09769 Human
- Unigene: 1422 Human
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Alternative names
- c fgr antibodyc fgr protooncogene antibodyc src 2 proto oncogene antibody
- c src2 antibodyFGR antibodyFLJ43153 antibodyGardner Rasheed feline sarcoma viral (v fgr) antibodyGardner Rasheed feline sarcoma viral (v fgr) oncogene homolog antibodyMGC75096 antibodyp55 c fgr protein antibodyP55 FGR antibodyp55c fgr antibodyp58c fgr antibodyProto oncogene c Fgr antibodyProto oncogene tyrosine protein kinase FGR antibodySRC 2 antibodySRC2 antibodyTyrosine protein kinase Fgr antibody
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Anti-FGR antibody images
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IHC-P - FGR antibody (ab58228)FGR antibody (ab58228) used in immunohistochemistry at 3ug/ml on formalin fixed and paraffin embedded human lymph node. -
Western blot - FGR antibody (ab58228)
Predicted band size : 59 kDa
FGR antibody (ab58228) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-FGR antibody (ab58228)
ab58228 has not yet been referenced specifically in any publications.
