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Western blot - FH antibody (ab58232)
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Product Name
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FH antibody
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See all FH antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to FH
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Immunogen
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Recombinant full length protein, corresponding to amino acids 33-511 of Human FH
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Reacts with
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Hu
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Tested applications
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WB
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Abreviews
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Application notes
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic and Mitochondrial
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Signal Transduction >> Metabolism >> Energy Metabolism
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Relevance
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FH (Fumarate hydratse) catalyzes the conversion of fumarate to malate. It is a key enzyme in the tricarboxylic acid (TCA) cycle. It exists in a cytosolic form and an N terminal extended form. The N terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. FH also acts as a tumor suppressor.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this FH antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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FH antibody images:
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 Western blot - FH antibody (ab58232)
Predicted band size : 55 kDa
FH antibody (ab58232) at 1ug/lane + HeLa cell lysate at 25ug/lane.
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References for FH antibody (ab58232)
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This product has been used in:
Kienhfer J et al. Association of mitochondrial antioxidant enzymes with mitochondrial DNA as integral nucleoid constituents. FASEB J : (2009). PubMed: 19228881
If you publish research using ab58232 please let us know so that we can cite the reference on this datasheet.
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Search PubMed (MEDLINE) for references to FH
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FH antibody - more information
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Customer reviews (feedback) regarding FH antibody |
Customer FAQs regarding FH antibody |
Protocols for FH antibody |
Price and availability of products related to FH antibody |
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FH antibody - other tools:
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Contact Abcam with a Technical Enquiry about FH antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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