|
|
|
|
|
Product Name
|
FHIT antibody
|
| |
See all FHIT antibodies (5)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to FHIT
|
|
Immunogen
|
Synthetic peptide mapping to the N terminus of Human FHIT.
|
|
Reacts with
(species key)
|
Hu, Ms, Rat
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: Use at a concentration of 1 - 4 µg/ml. Detects a band of approximately 16 kDa (predicted molecular weight: 17 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
293 cell lysates.
|
|
Cellular localization
|
Cytoplasmic
|
|
Research areas
|
Chromatin and Nuclear Signaling >> Transcription >> Cancer susceptibility >> Tumor Suppressors
|
|
Relevance
|
FHIT (fragile histidine triad) cleaves adenosine 5' PPP 5' A to yield AMP and ADP. Alterations and deletions of the FHIT gene are strongly linked to the genesis and establishment of human tumors of the lung, cervix, breast, colon, stomach and pancreas. In normal cells, FHIT may act as a tumor suppressor. FHIT physically associates with ubiquitin conjugating enzyme 9.
|
|
|
|
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Purity
|
Immunogen affinity purified
|
|
Storage buffer
|
Preservative: 0.02% Thimerosal (merthiolate).
Constituents: 50% Glycerol, 1% BSA, PBS. Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Thimerosal MSDS
|
|
Form
|
Liquid
|
|
Concentration
|
0.500 mg/ml
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this FHIT antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
| |
|
Search PubMed (MEDLINE) for references to FHIT
|
| |
FHIT antibody - more information
|
Customer reviews (feedback) regarding FHIT antibody |
Customer FAQs regarding FHIT antibody |
Protocols for FHIT antibody |
Price and availability of products related to FHIT antibody |
| |
FHIT antibody - related products:
|
|
|
| |
FHIT antibody - other tools:
|
Contact Abcam with a Technical Enquiry about FHIT antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
