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Anti-FSH beta 2 antibody [INN-hFSH-60] (ab49488)

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Overview

Product name

Anti-FSH beta 2 antibody [INN-hFSH-60]

Description

Mouse monoclonal [INN-hFSH-60] to FSH beta 2

Specificity

Reacts with the beta 2 epitope of the beta subunit. Not cross-reactive with human thyroid stimulating hormone, human luteinising hormone, human chorionic gonadotrophin, alpha human chorionic gonadotrophin and alpha human follicle stimulating hormone.

Tested applications

IHC-Fr, IHC-Pmore details

Cross reactivity

Reacts with

Human

Immunogen

Human follicle stimulating hormone.

Positive control

Human pituitary gland.

Properties

Form

Liquid

Storage instructions

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 15mM Sodium Azide
Constituents: Tissue culture supernatant

Purity

Tissue culture supernatant

Clonality

Monoclonal

Clone number

INN-hFSH-60

Myeloma

P3x63-Ag8.653

Isotype

IgG1

Research areas

Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Hormone biosynthesis
Signal Transduction >> Growth Factors/Hormones >> Hormones

Applications

Show applications key

Our Abpromise guarantee covers the use of ab49488 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • IHC-Fr

     

  • IHC-P

     

Application notes

IHC-P: 1/25 - 1/50. Trypsin digestion of paraffin sections is recommended.
IHC-Fr: 1/25 - 1/50.


Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Follicle stimulating hormone (FSH) is a glycoprotein hormone of 35kD which is involved in the maturation of ovarian follicles and stimulation of estrogen secretion. In males, FSH stimulates the secretion of testosterone. It is a heterodimer with an alpha chain shared by thyrotropin, lutropin, follitropin and gonadotropin, and a unique beta chain. It is expressed in gonadotropic cells of the pituitary. FSH is used in the treatment of infertility in women with proven hypopituitarism and in superovulation treatment for assisted conception. In men it is used for the stimulation of spermatogenesis.

Cellular localization

Secreted

Alternative names

  • Follicle stimulating hormone subunit beta antibody
  • follicle stimulating hormone, beta polypeptide antibody
  • follitropin antibody
  • Follitropin beta chain precursor antibody
  • FSH B antibody
  • FSH beta antibody
see all

Database links

References for Anti-FSH beta 2 antibody [INN-hFSH-60] (ab49488)

ab49488 has not yet been referenced specifically in any publications.

Publishing research using ab49488? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"