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Product Name
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Factor X antibody
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See all Factor X antibodies (8)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to Factor X
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Immunogen
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Full length native purified Human Factor X
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Reacts with
(species key)
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Hu
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Specificity
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This antibody recognizes the heavy chains of human factors Xa and X; it does not bind bovine factor X or BEGRck-Xa.
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Tested applications
(see key)
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ELISA, P, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
P: Use at an assay dependent dilution.
This antibody inhibits PT, prothrombinase and partially APTT, but not amidase activity.
WB: Use at an assay dependent dilution. Predicted molecular weight: 55 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Cardiovascular >> Blood >> Coagulation >> Extrinsic
Cardiovascular >> Blood >> Coagulation >> Intrinsic
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Relevance
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Factor X is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a haemorrhagic condition of variable severity.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG1
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Purity
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Ion Exchange Chromatography
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Storage buffer
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Preservative: None
Constituents: 50% (v/v)Glycerol/water Material safety datasheet (MSDS) for this product:
Glycerol MSDS
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Purification notes
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Salt fractionation followed by gel filtration and ion exchange chromatography.
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Form
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Liquid
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Concentration
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7.600 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Factor X antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to Factor X
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Factor X antibody - more information
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Customer reviews (feedback) regarding Factor X antibody |
Customer FAQs regarding Factor X antibody |
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Price and availability of products related to Factor X antibody |
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Contact Abcam with a Technical Enquiry about Factor X antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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