Anti-Factor Xa antibody (ab111171)
- Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- Storage bufferpH: 7.50
Preservative: 0.02% Sodium azide
Constituents: PBS, 50% Glycerol
- Concentration information loading...
- PurityProtein G purified
- Clonality Polyclonal
- Research Areas
Our Abpromise guarantee covers the use of ab111171 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||WB: Use at an assay dependent dilution. Predicted molecular weight: 55 kDa.|
|ELISA||ELISA: Use at an assay dependent dilution.|
- FunctionFactor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
- Tissue specificityPlasma; synthesized in the liver.
- Sequence similaritiesBelongs to the peptidase S1 family.
Contains 2 EGF-like domains.
Contains 1 Gla (gamma-carboxy-glutamate) domain.
Contains 1 peptidase S1 domain.
modificationsThe vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
N- and O-glycosylated.
The activation peptide is cleaved by factor IXa (in the intrinsic pathway), or by factor VIIa (in the extrinsic pathway).
The iron and 2-oxoglutarate dependent 3-hydroxylation of aspartate and asparagine is (R) stereospecific within EGF domains.
- Cellular localizationSecreted.
- Activated factor Xa heavy chain antibodyCoagulation factor X antibodyF10 antibody
- FA10_HUMAN antibodyFX antibodyFXA antibodyProthrombinase antibodyStuart factor antibodyStuart Prower factor antibodyStuart-Prower factor antibody
References for Anti-Factor Xa antibody (ab111171)
ab111171 has not yet been referenced specifically in any publications.