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Products:Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Overview
Product name
Anti-FABP4 antibody
See all FABP4 products (18) ...
Description
Rabbit polyclonal to FABP4
Specificity
ab23693 recognises FABP4 (ALBP).
Tested applications
ICC/IF, WBmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Predicted to work with
Rabbit, Hamster
Immunogen
Synthetic peptide: TTIKRKREDDKLVVE, corresponding to amino acids 103/118 of Human FABP4
TTIKRKREDD KLVVE
Positive control
Rat brown fat.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, 0.1% BSA, Tris buffered saline, pH 7.4
Concentration
Concentration information loading...
Purity
Protein A purified
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Stem Cells >> Mesenchymal Stem Cells >> Adipogenesis
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
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Western blot - FABP4 antibody (ab23693)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab23693 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ICC/IF: Use a concentration of 4 µg/ml
WB: Use a concentration of 2 µg/mlDetects a band of approximately 15 kDa (predicted molecular weight: 15 kDa).
Target
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Sequence similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Cellular localization
Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Target information above from: UniProt accessionP15090
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- adipocyte antibody
- 3T3-L1 lipid-binding protein antibody
- 422/aP2 antibody
see all
Database links
- Entrez Gene: 2167 Human
- Entrez Gene: 11770 Mouse
- Entrez Gene: 79451 Rat
- Omim: 600434 Human
- SwissProt: P15090 Human
- SwissProt: P04117 Mouse
- SwissProt: P70623 Rat
- Unigene: 391561 Human
see all
Anti-FABP4 antibody images:
Western blot - FABP4 antibody (ab23693)
All lanes : Anti-FABP4 antibody (ab23693) at 2 µg/ml
Lane 1 : His-tagged recombinant rat ALBP lysate (1ug)
Lane 2 : rat brown fat (30ug)
Predicted band size : 15 kDa
Observed band size : 15 kDa
References for Anti-FABP4 antibody (ab23693)
ab23693 has not yet been referenced specifically in any publications.
Publishing research using ab23693? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"