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Products:Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
Overview
Product name
Anti-FABP4 antibody
See all FABP4 products (18) ...
Description
Mouse monoclonal to FABP4
Tested applications
Cross reactivity
Reacts with
Recombinant Fragment
Predicted to work with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-133 of Human FABP4.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG1
Light chain type
kappa
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Metabolism of lipids and lipoproteins
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Metabolism
Stem Cells >> Mesenchymal Stem Cells >> Adipogenesis
Signal Transduction >> Metabolism >> Lipid metabolism
Cardiovascular >> Lipids / Lipoproteins >> Fatty Acids >> Binding proteins
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Western blot - FABP4 antibody (ab54617)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab54617 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus.
Sequence similarities
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Domain
Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
Cellular localization
Cytoplasm. Nucleus. Depending on the nature of the ligand, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus. Subject to constitutive nuclear export.
Target information above from: UniProt accessionP15090
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- adipocyte antibody
- 3T3-L1 lipid-binding protein antibody
- 422/aP2 antibody
see all
Database links
- Entrez Gene: 2167 Human
- Omim: 600434 Human
- SwissProt: P15090 Human
- Unigene: 391561 Human
Anti-FABP4 antibody images:
Western blot - FABP4 antibody (ab54617)
Western blot against tagged recombinant protein immunogen using ab54617 FABP4 antibody at 1ug/ml. Predicted band size of immunogen is 40 kDa.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
References for Anti-FABP4 antibody (ab54617)
This product has been referenced in:
- Buers Iet al. TIP47, a lipid cargo protein involved in macrophage triglyceride metabolism. Arterioscler Thromb Vasc Biol 29:767-73 (2009).Read more (PubMed: 19286631) »
See 1 publication for this product
Publishing research using ab54617? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"