Anti-Fc epsilon RI antibody (ab34362)

Overview

• Product nameAnti-Fc epsilon RI antibodySee all Fc epsilon RI primary antibodies ...
• Description
  Rabbit polyclonal to Fc epsilon RI
• SpecificityRecognizes and is specific for human TCR, Fc Receptor, gamma subunit (~10kD).
• Tested applicationsWB, IP more details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  Synthetic peptide: KHEKPPQ, corresponding to amino acids aa80-86 of Human Fc epsilon RI

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Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: 0.05% Sodium Azide
  Constituents: 30% Glycerol, 0.15M Sodium chloride, 0.1M Tris glycine. pH 7.4
• Concentration information loading...
• PurityProtein A purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Immunology
  • Immunoglobulins
  • Heavy Chain
  • IgE

  • Immunology
  • Immunoglobulins
  • Receptors

Applications

Target

• FunctionBinds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
• Sequence similaritiesContains 2 Ig-like (immunoglobulin-like) domains.
• Cellular localizationCell membrane.

Target information above from: UniProt accession P12319 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 2205 Human
  • Entrez Gene: 14125 Mouse
  • Entrez Gene: 25047 Rat
  • Omim: 147140 Human
  • SwissProt: P12319 Human
  • SwissProt: P20489 Mouse
  • SwissProt: P12371 Rat
  • Unigene: 897 Human

  • Unigene: 5266 Mouse
  • Unigene: 9677 Rat

  see all

• Alternative names
  Fc epsilon RI alpha antibodyFc epsilon RI alpha chain antibodyFc epsilon RI alpha-chain antibody

  Fc fragment of IgE high affinity I receptor for alpha polypeptide antibodyFc fragment of IgE, high affinity I, receptor for, alpha subunit antibodyFc fragment of IgE, high affinity I, receptor for; alpha polypeptide antibodyFc IgE receptor alpha polypeptide antibodyFc IgE receptor, alpha chain antibodyFc IgE receptor, alpha polypeptide antibodyFc of IgE high affinity I receptor for alpha polypeptide antibodyFc-epsilon RI-alpha antibodyFCE 1A antibodyFCE1A antibodyFCER 1A antibodyFCER 1A antibodyFCER1A antibodyFCERA_HUMAN antibodyFceRI alpha antibodyFcERI antibodyhigh affinity IgE receptor antibodyHigh affinity immunoglobulin epsilon receptor alpha subunit antibodyhigh affinity immunoglobulin epsilon receptor alpha-subunit antibodyHigh affinity immunoglobulin epsilon receptor subunit alpha antibodyIgE Fc receptor alpha subunit antibodyIgE Fc receptor alpha subunit antibodyIgE Fc receptor subunit alpha antibodyImmunoglobulin E receptor high affinity of mast cells alpha polypeptide antibodyimmunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide antibody

  see all

Anti-Fc epsilon RI antibody images

• 

  Western blot - Fc epsilon RI antibody (ab34362)
  All lanes : Anti-Fc epsilon RI antibody (ab34362)
  
  Lane 1 : Lysates prepared from Caco2/TC7 subconfluent cell line.
  Lane 2 : Lysates prepared from Caco2/TC7 confluent cell line.
  Lane 3 : Lysates prepared from HCT8 subconfluent cell line.
  Lane 4 : Lysates prepared from HCT8 confluent cell line.
  Lane 5 : Lysates prepared from RBL transfected cells.
  
  
  Predicted band size : 10 kDa
  

  Image from Untersmayr E et al, PLoS One. 2010 Feb 2;5(2):e9023, Fig 8.