Anti-Ferritin Heavy Chain antibody (ab36660)

Overview

• Product nameAnti-Ferritin Heavy Chain antibodySee all Ferritin Heavy Chain primary antibodies ...
• Description
  Chicken polyclonal to Ferritin Heavy Chain
• Tested applicationsWB, ELISA more details
• Species reactivity
  Reacts with: Mouse, Human
  
• Immunogen

  Synthetic peptide, corresponding to amino acids 1-182 of Human Ferritin Heavy Chain

• Positive controlELISA: Purified Human Ferritin protein.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgY
• Research Areas
  • Metabolism
  • Pathways and Processes
  • Cofactors, Vitamins / minerals
  • Vitamins / minerals

  • Metabolism
  • Types of disease
  • Neurodegenerative disease

  • Metabolism
  • Types of disease
  • Cancer

  • Signal Transduction
  • Metabolism
  • Vitamins / Minerals

  • Cardiovascular
  • Blood
  • Serum Proteins

  • Neuroscience
  • Neurology process
  • Neurodegenerative disease
  • Alzheimer's disease
  • Other

Applications

Target

• RelevanceFerritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy; 21 kDa) and L (light; 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.
• Cellular localizationCytoplasmic
• Database links
  • Entrez Gene: 2495 Human
  • Entrez Gene: 2495 Human
  • Entrez Gene: 2495 Human
  • Entrez Gene: 14319 Mouse
  • Omim: 134770 Human
  • SwissProt: P02794 Human
  • SwissProt: P02794 Human
  • SwissProt: P02794 Human

  • SwissProt: P09528 Mouse

  see all

• Alternative names
  Apoferritin antibodyCell proliferation inducing gene 15 protein antibodyF HC antibody

  Ferritin H subunit antibodyFerritin heavy chain antibodyFerritin heavy polypeptide 1 antibodyFHC antibodyFRIH antibodyFTH 1 antibodyFTH antibodyFTH1 antibodyFTH1 protein antibodyFTHL 6 antibodyFTHL6 antibodyIron overload autosomal dominant antibodyMGC104426 antibodyOK/SW-cl.84 antibodyPIG 15 antibodyPIG15 antibodyPlacenta immunoregulatory factor antibodyPLIF antibodyProliferation inducing gene 15 protein antibodyProliferation inducing protein 15 antibody

  see all

Anti-Ferritin Heavy Chain antibody images

• 

  ELISA - Ferritin Heavy Chain antibody (ab36660)
  Ab36660, at a fixed concentration of 1 µg/ml, staining Ferritin heavy chain from purified Ferritin protein by ELISA. Goat anti IgY HRP was the secondary antibody. A serial dilution of the antigen was used.