|
|
|
|
Western blot - Ferritin Heavy Chain antibody (ab71562)
(enlarge)
|
|
|
|
|
Product Name
|
Ferritin Heavy Chain antibody
|
| |
See all Ferritin Heavy Chain antibodies (7)...
|
|
Product type
|
Primary antibodies
|
|
Description
|
Rabbit polyclonal to Ferritin Heavy Chain
|
|
Immunogen
|
Synthetic Ferritin Heavy Chain Peptide
|
|
Reacts with
|
Hu, Ms
|
|
Does not react with
(species key)
|
Rat
|
|
Tested applications
(see key)
|
WB
|
|
|
Abreviews
|
|
|
|
Application notes
(see key)
|
Recommended dilutions
WB: 1/2000. Detects bands of approximately 21 and 42 kDa (predicted molecular weight: 21 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
|
|
Positive control
(see definition)
|
U87mg and Hela cell lysate
|
|
Cellular localization
|
Cytoplasmic
|
|
Research areas
|
Signal Transduction >> Metabolism >> Vitamins / Minerals
Cardiovascular >> Blood >> Serum Proteins
Neuroscience >> Neurology process >> Neurodegenerative disease >> Alzheimer's disease >> Other
|
|
Relevance
|
Ferritin is a ubiquitous and highly conserved protein which plays a major role in iron homeostasis by sequestering and storing iron in a non-toxic and soluble form. It forms a holoenzyme of ~450 kDa, consisting of 24 subunits of two types, H (heavy; 21 kDa) and L (light; 19 kDa), and is capable of storing up to 4,500 atoms of ferric iron. Depending on the tissue type and physiological status of the cell, the ratio of H to L subunits in ferritin can vary widely. Ferritin is found in the liver, spleen, kidney and heart, with smaller amounts being found in blood. Serum ferritin levels serve as an indicator of the amount of iron stored in the body. Serum ferritin is the most sensitive test for anaemia, and is also used as a marker for restless leg syndrome, hemochromatosis and porphyria. As ferritin is an acute-phase reactant, it is often elevated during infection. Defects in ferritin proteins are associated with several neurodegenerative diseases.
|
|
|
Ferritin Heavy Chain antibody (ab71562) |
|
Database links
|
The links below go to external sites and will open in a new browser window |
|
Raised in
|
Rabbit
|
|
Clonality
|
Polyclonal
|
|
Isotype
|
IgG
|
|
Storage buffer
|
Preservative: 0.03% Sodium Azide
Constituents: 50% Glycerol, 0.01% BSA, HEPES, 0.15M Sodium chloride Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Sodium Azide MSDS
|
|
Form
|
Liquid
|
|
Storage instructions
|
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
|
| |
At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this Ferritin Heavy Chain antibody is on this datasheet. But please do contact us if you would like any reassurance! |
 |
|
|
See below for Ferritin Heavy Chain antibody images, references, products related to ab71562 and other tools.
|
| |
Ferritin Heavy Chain antibody images:
|
 Western blot - Ferritin Heavy Chain antibody (ab71562)
All lanes : Ferritin Heavy Chain antibody (ab71562) at 1/2000 dilution
Lane 1 : U87mg cell lysate
Lane 2 : Hela cell lysate
Predicted band size : 21 kDa
Observed band size : 21 kDa
Additional bands at : 42 kDa. We are unsure as to the identity of these extra bands.
|
| |
| |
|
Search PubMed (MEDLINE) for references to Ferritin Heavy Chain
|
| |
Ferritin Heavy Chain antibody - more information
|
Customer reviews (feedback) regarding Ferritin Heavy Chain antibody |
Customer FAQs regarding Ferritin Heavy Chain antibody |
Protocols for Ferritin Heavy Chain antibody |
Price and availability of products related to Ferritin Heavy Chain antibody |
| |
Ferritin Heavy Chain antibody - related products:
|
|
|
| |
Ferritin Heavy Chain antibody - other tools:
|
Contact Abcam with a Technical Enquiry about Ferritin Heavy Chain antibody |
| |
All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
