Anti-Ficolin 2 antibody [19] (ab56225)
Key features and details
- Mouse monoclonal [19] to Ficolin 2
- Suitable for: ELISA, IP, WB
- Reacts with: Human
- Isotype: IgG2a
Overview
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Product name
Anti-Ficolin 2 antibody [19]
See all Ficolin 2 primary antibodies -
Description
Mouse monoclonal [19] to Ficolin 2 -
Host species
Mouse -
Specificity
ab56225 reacts specifically with L Ficolin (Ficolin 2). No cross reactivity is seen with M Ficolin (Ficolin 1) and H Ficolin (Ficolin 3). -
Tested applications
Suitable for: ELISA, IP, WBmore details -
Species reactivity
Reacts with: Human -
Immunogen
Purified procaryot expressed recombinant human Ficolin 2 and full-length Ficolin 2 protein
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.097% Sodium azide
Constituents: 2.9% Sodium chloride, 0.0268% PBS -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
19 -
Myeloma
Sp2 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab56225 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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ELISA |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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WB |
Use at an assay dependent concentration.
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Notes |
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ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
Target
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Function
May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. -
Tissue specificity
Expressed by the liver and secreted in plasma. -
Sequence similarities
Belongs to the ficolin lectin family.
Contains 1 collagen-like domain.
Contains 1 fibrinogen C-terminal domain. -
Domain
The fibrinogen-like domain (FBG) contains potential calcium-binding sites that may be involved in carbohydrate binding. -
Cellular localization
Secreted. - Information by UniProt
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Database links
- Entrez Gene: 2220 Human
- Omim: 601624 Human
- SwissProt: Q15485 Human
- Unigene: 54517 Human
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Alternative names
- 37 kDa elastin-binding protein antibody
- Collagen/fibrinogen domain containing protein 2 antibody
- Collagen/fibrinogen domain-containing protein 2 antibody
see all
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (1)
ab56225 has been referenced in 1 publication.
- Rodríguez-Gallego E et al. Proteomic Profile Associated With Loss of Spontaneous Human Immunodeficiency Virus Type 1 Elite Control. J Infect Dis 219:867-876 (2019). PubMed: 30312441