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Overview

  • Product nameAnti-Flotillin 2 antibodySee all Flotillin 2 primary antibodies ...
  • Description
    Mouse polyclonal to Flotillin 2
  • Tested applicationsWB, IHC-P more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Full length human Flotillin 2 protein

  • Positive controlHuman liver lysate, Flotillin 2 transfected 293T cell lysate and Human prostate tissue

Properties

Applications

Our Abpromise guarantee covers the use of ab88498 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB
IHC-P
  • Application notesIHC-P: Use at a concentration of 1.5 µg/ml.
    WB: 1/500 - 1/1000. Predicted molecular weight: 47 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.

    • Target

    • FunctionMay act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. May be involved in epidermal cell adhesion and epidermal structure and function.
    • Tissue specificityIn skin, expressed in epidermis and epidermal appendages but not in dermis. Expressed in all layers of the epidermis except the basal layer. In hair follicles, expressed in the suprabasal layer but not the basal layer. Also expressed in melanoma and carcinoma cell lines, fibroblasts and foreskin melanocytes.
    • Sequence similaritiesBelongs to the band 7/mec-2 family. Flotillin subfamily.
    • Cellular localizationCell membrane. Membrane > caveola. Endosome. Membrane-associated protein of caveolae.

      • Target information above from: UniProt accession Q14254 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt
    • Database links
      • Alternative names
          ECS-1 antibodyECS1 antibodyEpidermal surface antigen 1 antibody
          Epidermal surface antigen antibodyESA antibodyESA1 antibodyFLOT2 antibodyFLOT2_HUMAN antibodyFlotillin-2 antibodyM17S1 antibodyMembrane component chromosome 17 surface marker 1 antibodyMembrane component chromosome 17 surface marker 1 homolog antibodyMembrane component, chromosome 17, surface marker 1 antibodyREG-1 antibodyReggie-1 antibodyReggie-2 antibody
        see all

      Anti-Flotillin 2 antibody images

      • Western blot - Flotillin 2 antibody (ab88498)
        Western blot - Flotillin 2 antibody (ab88498)
        Anti-Flotillin 2 antibody (ab88498) at 1/500 dilution + Human Liver lysate at 50 µg

        Predicted band size : 47 kDa
      • Western blot - Flotillin 2 antibody (ab88498)
        Western blot - Flotillin 2 antibody (ab88498)
        All lanes : Anti-Flotillin 2 antibody (ab88498) at 1/500 dilution

        Lane 1 : 293T cell lysate Flotillin 2 transfected
        Lane 2 : 293T cell lysate non-transfected

        Lysates/proteins at 25 µg per lane.


        Predicted band size : 47 kDa
      • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Flotillin 2 antibody (ab88498)
        Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Flotillin 2 antibody (ab88498)
        ab88498 at 1.5µg/ml in Human prostate by IHC

      References for Anti-Flotillin 2 antibody (ab88498)

      ab88498 has not yet been referenced specifically in any publications.

      Publishing research using ab88498 ? Please let us know so that we can cite the reference in this datasheet

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