Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Immunology >> Cell Type Markers >> CD >> Non-lineage
Overview
Product name
Anti-Follicular Dendritic Cells antibody [ED5]
See all Follicular Dendritic Cells products (5) ...
Description
Mouse monoclonal [ED5] to Follicular Dendritic Cells
Specificity
We have data to indicate that this antibody may not cross react with Mouse. However, this has not been conclusively tested and expression levels may vary in certain cell lines/tissues.
Tested applications
IHC-Frmore details
Cross reactivity
Reacts with
Rat
Immunogen
Rat spleen cells.
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Primary antibody notes
ED5 staining reveals a web like pattern in B cell follicles, representing the follicular dendritic cells. Mesangial cells in the kidney are also ED5 positive.
Clonality
Monoclonal
Clone number
ED5
Myeloma
Sp2/0-Ag14
Isotype
IgG1
Research areas
Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
Immunology >> Cell Type Markers >> Non-CD >> APC
Immunology >> Cell Type Markers >> CD >> Non-lineage
Applications
Show applications key
Our Abpromise guarantee covers the use of ab33781 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
IHC-Fr: 1/260IHC-Fr: 1/260
Target
Relevance
Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.
Alternative names
- FDC antibody
- FDCs antibody
- Follicular dendritic cell antibody
References for Anti-Follicular Dendritic Cells antibody [ED5] (ab33781)
This product has been referenced in:
- Jeurissen SH & Dijkstra CD Characteristics and functional aspects of nonlymphoid cells in rat germinal centers, recognized by two monoclonal antibodies ED5 and ED6. Eur J Immunol 16:562-8 (1986).Read more (PubMed: 3486130) »
See 1 publication for this product
Publishing research using ab33781? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"