Follicular Dendritic Cells antibody [Ki-M4 ] (ab15628)

Product Name 

Follicular Dendritic Cells antibody [Ki-M4 ]

Product type 

Primary antibodies

Description 

Mouse monoclonal [Ki-M4 ] to Follicular Dendritic Cells

Immunogen 

Circulating immune complexes of a patient with Hodgkin's disease (Human).

Reacts with 
(species key)

Hu

Specificity 

ab15628 recognises dendritic reticulum cells, lining cells of lymph node sinuses, and a small fraction of monocytes. The antibody does not cross-react with epithelial and mesenchymal cells, including macrophages and other cells from bronchial and peritoneal lavages. ab15628 does not react with any circulating cell.

Epitope 

ab15628 detects an epitope within a proteoglycan localized on the cell surface.

Tested applications 
(see key)

IHC-Fr

Abreviews 

Customer reviews (see key)

Read about Abreviews

Application notes 
(see key)

Recommended dilutions
IHC-Fr: Use at a concentration of 0.5 µg/ml (1:400).

Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.

Research areas 

Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
Immunology >> Cell Type Markers >> Non-CD >> APC
Immunology >> Cell Type Markers >> CD >> Non-lineage

Relevance 

Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.

Raised in 

Mouse

Clonality 

Monoclonal

Clone number 

Ki-M4

Isotype 

IgG2a

Purity 

Protein G purified

Storage buffer 

Preservative: 0.02% Sodium Azide
Constituents: PBS, 10mg/ml BSA. pH 7.2

Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS

Form 

Liquid

Concentration 

0.200 mg/ml

Storage instructions 

Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.

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