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Products:Immunology >> Cell Type Markers >> CD >> Non-lineage
Overview
Product name
Anti-Follicular Dendritic Cells antibody [Ki-M4 ]
See all Follicular Dendritic Cells products (5) ...
Description
Mouse monoclonal [Ki-M4 ] to Follicular Dendritic Cells
Specificity
ab15628 recognises dendritic reticulum cells, lining cells of lymph node sinuses, and a small fraction of monocytes. The antibody does not cross-react with epithelial and mesenchymal cells, including macrophages and other cells from bronchial and peritoneal lavages. ab15628 does not react with any circulating cell.
Tested applications
IHC-Frmore details
Cross reactivity
Reacts with
Human
Immunogen
Circulating immune complexes of a patient with Hodgkin's disease (Human).
Epitope
ab15628 detects an epitope within a proteoglycan localized on the cell surface.
Properties
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: PBS, 10mg/ml BSA. pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Clone number
Ki-M4
Isotype
IgG2a
Research areas
Tags & Cell Markers >> Cell Type Markers >> Other Cell Types
Immunology >> Cell Type Markers >> Non-CD >> APC
Immunology >> Cell Type Markers >> CD >> Non-lineage
Applications
Show applications key
Our Abpromise guarantee covers the use of ab15628 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-Fr
Application notes
IHC-Fr: Use at a concentration of 0.5 µg/ml (1:400).
Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Relevance
Follicular dendritic cells are cells that facilitate antigen recognition by B cells in follicles. This kind of dendritic cell is not bone marrow derived and is not a kind of blood cell. It is purely a resident of the follicles of secondary lymphoid organs. B cells form germinal centers around follicular dendritic cells in lymphoid organs. Dendritic cells form from monocytes, white blood cells which circulate in the body and, depending on the right signal, can turn into dendritic cells or macrophages. The monocytes in turn are formed from stem cells in the bone marrow.
Alternative names
- FDC antibody
- FDCs antibody
- Follicular dendritic cell antibody
References for Anti-Follicular Dendritic Cells antibody [Ki-M4 ] (ab15628)
ab15628 has not yet been referenced specifically in any publications.
Publishing research using ab15628? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"