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Overview

  • Product nameAnti-G-CSF antibodySee all G-CSF primary antibodies ...
  • Description
    Rabbit polyclonal to G-CSF
  • Tested applicationsWB, ELISA, Neutralising more details
  • Species reactivity
    Reacts with: Mouse
  • Immunogen

    Highly pure (>98%) recombinant mG-CSF (mouse Granulocyte Colony Stimulating Factor ).

Properties

  • FormLyophilised:Reconstitute with 200µl of sterile water. Please note that if you receive this product in liquid form it has already been reconstituted as described and no further reconstitution is necessary.
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
  • Storage bufferPBS, pH 7.4, no preservative, sterile filtered
  • Concentration information loading...
  • PurityImmunogen affinity purified
  • Clonality Polyclonal
  • Isotypeunknown
  • Light chain typeunknown
  • Research Areas

Applications

Our Abpromise guarantee covers the use of ab9751 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 0.1 - 0.2 µg/ml.
ELISA ELISA: Use a concentration of 0.5 µg/ml. Allows the detection of 0.2 - 0.4 ng/well of recombinant mG-CSF (using 100µl/well antibody solution).
Neutralising Neut: Use a concentration of 0.005 - 0.01 µg/ml. for one-half maximal inhibition [ND50] of the biological activity of mG-CSF (0.5 ng/ml).

Target

  • FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
  • Sequence similaritiesBelongs to the IL-6 superfamily.
  • Post-translational
    modifications    O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P09919 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        Colony stimulating factor 3 (granulocyte) antibodyCSF 3 antibodyCSF beta antibody
        CSF3 antibodyCSF3_HUMAN antibodyCsfg antibodyFilgrastim antibodyG-CSF antibodyGCSA antibodyGCSF antibodyGranulocyte colony stimulating factor antibodyGranulocyte colony-stimulating factor antibodyLenograstim antibodyMacrophage granulocyte inducer 2 antibodyMGC45931 antibodyMGI 2 antibodyPluripoietin antibody
      see all

    References for Anti-G-CSF antibody (ab9751)

    This product has been referenced in:
    • Liu Y  et al. Interacting neuroendocrine and innate and acquired immune pathways regulate neutrophil mobilization from bone marrow following hemorrhagic shock. J Immunol 182:572-80 (2009). ELISA, Neutralising ; Mouse . Read more (PubMed: 19109190) »

    See 1 Publication for this product

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