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Overview

  • Product nameG-CSF protein (Active)See all G-CSF proteins and peptides ...
  • Protein descriptionRecombinant full length protein
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • Purification notesSterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses.
  • Biological activityThe ED50, determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells, is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107 units/mg.
  • FormLyophilised
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Concentration information loading...
  • Sequence notesHuman G-CSF is a 18.7 kDa protein containing 174 amino acid residues: TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA LQEKLCATYK LCHPEE LVLL GHSLGIPWAPLSSCPSQALQ LAGCLSQLHS GLF LYQGLLQ ALEGISPELG PTLDTLQLDV ADFATTIWQQ MEELGMAPAL QPTQGAMPAF ASAFQRRAGG VLVASHL QSF LEVSYRVLRH LAQP
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab9692 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution. This protein can be used with studies using ab9691 and ab18627.
  • Application notesThis peptide can be used with studies using ab9691 and ab18627.

    • Protein info

    • Alternative names
        Colony stimulating factor 3 (granulocyte)CSF 3CSF beta
        CSF3CSF3_HUMANCsfgFilgrastimG-CSFGCSAGCSFGranulocyte colony stimulating factorGranulocyte colony-stimulating factorLenograstimMacrophage granulocyte inducer 2MGC45931MGI 2Pluripoietin
      see all
  • FunctionGranulocyte/macrophage colony-stimulating factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. This CSF induces granulocytes.
  • Sequence similaritiesBelongs to the IL-6 superfamily.
  • Post-translational
    modifications    O-glycan consists of Gal-GalNAc disaccharide which can be modified with up to two sialic acid residues (done in recombinantly expressed G-CSF from CHO cells).
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P09919 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for G-CSF protein (Active) (ab9692)

    ab9692 has not yet been referenced specifically in any publications.

    Publishing research using ab9692 ? Please let us know so that we can cite the reference in this datasheet

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    I am interested in ordering recombinant human G-CSF from you. However,there are two products that describe the peptide as "Highly pure (>98%) recombinant hIL-11 (human Interleukin-11)". ab9752 has the recombinant murine sequence whereas ab9692 has the h...

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    Thank you for your email. There was a mistake on the datasheets for these proteins - ab9692 is recombinant human G-CSF and ab9752 is recombinant mouse G-CSF. They are not IL-ll proteins. I have updated the online datasheets to reflect this informati...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"