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Overview
Product name
G9a peptide
See all KMT1C / G9a products (2) ...
Protein description
Synthetic peptide derived from within residues 1 - 100 of Human G9a.(Note: the amino acid sequence is proprietary)This peptide was used as an immunogen for ab31874 - G9a antibody.
Protein length
1263 amino acids
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Information available upon request.
Concentration
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Research areas
Developmental Biology >> Embryogenesis >> Embryonic stem cells >> Intracellular
Developmental Biology >> Reproduction >> Germ cell markers
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation >> Lysine methylation
Stem Cells >> Germline Stem Cells >> Embryonic Germ Cells
Stem Cells >> Embryonic Stem Cells >> Intracellular
Epigenetics and Nuclear Signaling >> Chromatin Modifying Enzymes >> Methylation
Applications
Application notes
This peptide can be used with studies using ab31874.
Protein info
Relevance
KMT1C / G9a is a histone methytransferase that preferentially methylates K9 and K27 of histone H3 in vitro. H3 K9 methylation serves as a mark for epigenetic transcriptional repression by recruiting HP1 to the site of this post-translational modification. The binding of HP1 also may serve to recruit Dnmt3a/b, resulting in DNA methylation. G9a-mediated histone methylation plays a significant role in epigenetic silencing.
Cellular localization
Nuclear
References for G9a peptide (ab31873)
ab31873 has not yet been referenced specifically in any publications.
Publishing research using ab31873? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"