![Western blot - GAB1 antibody [Y423] (ab32093) image](#ab32093_1.jpg)
![Immunofluorescence - GAB1 antibody [Y423] (ab32093) image](#ab32093_2.jpg)
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Product name
Anti-GAB1 antibody [Y423]
See all GAB1 products (12) ...
Description
Rabbit monoclonal [Y423] to GAB1
Specificity
This antibody is specific for the splice isoform 2 of human GAB1.
Tested applications
WB, ICC/IFmore details
Cross reactivity
Reacts with
Mouse, Rat, Human
Immunogen
Synthetic peptide corresponding to residues in Human GAB1.
Positive control
293 cell lysate.
General notes
Produced under U.S. Patent No. 5,675,063.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Concentration
Concentration information loading...
Purity
IgG fraction
Clonality
Monoclonal
Clone number
Y423
Isotype
IgG
Research areas
Cancer >> Signal transduction >> Other
Cancer >> Cell cycle >> Cell differentiation
Cell Biology >> Cell Cycle >> Cell differentiation
Signal Transduction >> Adapters >> Cytoplasmic
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> MAPK Pathway
Cell Biology >> Apoptosis >> Intracellular >> Kinases
Applications
Show applications key
Our Abpromise guarantee covers the use of ab32093 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
ICC/IF
Application notes
ICC/IF: 1/50.
WB: 1/1000 - 1/5000. Predicted molecular weight: 76 kDa.
Is unsuitable for FACS, IHC or IP.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Probably involved in EGF and insulin receptor signaling.
Sequence similarities
Belongs to the GAB family.
Contains 1 PH domain.
Post-translational
modifications
Phosphorylated on tyrosine residue(s) by the epidermal growth factor receptor (EGFR) and the insulin receptor (INSR). Tyrosine phosphorylation of GAB1 mediates interaction with several proteins that contain SH2 domains.
Target information above from: UniProt accessionQ13480
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Gab 1 antibody
- Gab1 antibody
- Gab1 antibody
see all
Database links
- Entrez Gene: 2549 Human
- Entrez Gene: 14388 Mouse
- Entrez Gene: 361388 Rat
- Omim: 604439 Human
- SwissProt: Q13480 Human
- SwissProt: Q9QYY0 Mouse
- Unigene: 618456 Human
- Unigene: 80720 Human
see all
Anti-GAB1 antibody [Y423] images:
Western blot - GAB1 antibody [Y423] (ab32093)
![Western blot - GAB1 antibody [Y423] (ab32093)](/ps/datasheet/Images/32/ab32093/ab32093_1.jpg)
Anti-GAB1 antibody [Y423] (ab32093) at 1/5000 dilution + 293 cell lysate.
Predicted band size : 76 kDa
Observed band size : 76 kDa
Immunofluorescence - GAB1 antibody [Y423] (ab32093)
![Immunofluorescence - GAB1 antibody [Y423] (ab32093)](/ps/datasheet/Images/32/ab32093/ab32093_2.jpg)
ab32093 at a 1:50 dilution staining GAB1 in PC-12 cells using immunofluoresence
References for Anti-GAB1 antibody [Y423] (ab32093)
ab32093 has not yet been referenced specifically in any publications.
Publishing research using ab32093? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"