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Anti-GABA A Receptor alpha 1 antibody (ab32589)

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Overview

Product name

Anti-GABA A Receptor alpha 1 antibody
See all GABA A Receptor alpha 1 products (6) ...

Description

Rabbit polyclonal to GABA A Receptor alpha 1

Tested applications

WBmore details

Cross reactivity

Reacts with

Rat, Cow, Human

Immunogen

Fusion protein from the cytoplasmic loop of the alpha1-subunit of rat GABAA Receptor

Epitope

C-terminal cytoplasmic loop

Positive control

Rat, bovine, human and mouse brain extracts

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 50% Glycerol, 100µg/ml BSA, 150mM Sodium chloride, 10mM HEPES. pH 7.5

Concentration

Concentration information loading...

Purity

Immunogen affinity purified

Purification notes

Affinity purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Neuroscience >> Neurotransmission >> Receptors / Channels >> Ligand-Gated Ion Channels >> GABA Receptors
Neuroscience >> Neurotransmitter >> Amino Acids >> GABA

  • Western blot - GABA A Receptor alpha 1 antibody (ab32589)Western blot - GABA A Receptor alpha 1 antibody (ab32589) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab32589 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide1 Image

    WB

     WB: 1/1000Detects a band...Read more →

    WB: 1/1000Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

Target

Relevance

GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at Gamma aminobutyric acid type A (GABA A) receptors. GABA A receptors are ligand gated chloride ion channels. These receptors are believed to be pentameric hetero oligomers, for which 6 subunits are currently known (alpha, beta, gamma, delta, epsilon and rho). GABA A receptors mediate the majority of fast inhibitor synaptic transmissions in the brain. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA A receptor.

Cellular localization

Membrane; multi pass membrane protein.

Alternative names

  • EJM antibody
  • Gaba receptor alpha 1 polypeptide antibody
  • GABA(A) receptor subunit alpha 1 antibody
  • GABRA 1 antibody
  • GABRA1 antibody
  • Gamma aminobutyric acid (GABA) A receptor alpha 1 antibody
  • Gamma aminobutyric acid A receptor alpha 1 antibody
  • Gamma aminobutyric acid receptor subunit alpha 1 antibody
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Database links

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Anti-GABA A Receptor alpha 1 antibody images:

  Western blot - GABA A Receptor alpha 1 antibody (ab32589)

Western blot - GABA A Receptor alpha 1 antibody (ab32589)

All lanes : Anti-GABA A Receptor alpha 1 antibody (ab32589) at 1/1000 dilution

Lane 1 : Wildtype forebrain lysates 5-7 ug
Lane 2 : a1 knockout forebrain lysates 5-7 ug


Predicted band size : 51 kDa
Observed band size : 51 kDa

References for Anti-GABA A Receptor alpha 1 antibody (ab32589)

ab32589 has not yet been referenced specifically in any publications.

Publishing research using ab32589? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"