You have changed your country from  to  . Please be aware that this will change the currency in the purchasing process.

Reassurance, Refunds & Replacements

If your product does not perform as described on this datasheet, we will refund or replace your product...

Read our guarantee »
 

GADD45B protein (Human) (ab79246)

CodeSizePriceAbpointsAvailability
    
Add to basket
 
  • -
  •   
  •   
  •   
  •  
  •   
  •   
Updating...

Overview

Product name

GADD45B protein (Human)
See all GADD45B products (2) ...

Protein description

Recombinant full length human GADD45B; 160 amino acids, 17.8 kDa. Swiss ID = O75293.

Expression host

E. coli

Properties

Purity

>95% by SDS-PAGE

Purification notes

ab79246 is purified using conventional chromatography techniques.

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: None
Constituents: 20mM Tris HCl buffer, pH 7.5

Concentration

Concentration information loading...

Sequence notes

MTLEELVACD NAAQKMQTVT AAVEELLVAA QRQDRLTVGV YESAKLMNVD PDSVVLCLLA IDEEEEDDIA LQIHFTLIQS FCCDNDINIV RVSGMQRLAQ LLGEPAETQG TTEARDLHCL LVTNPHTDAW KSHGLVEVAS YCEESRGNNQ WVPYISLQER

Research areas

Cancer >> Oncoproteins/suppressors >> Oncoproteins >> Cell survival & death
Immunology >> Immune System Diseases >> Autoimmune
Signal Transduction >> Protein Phosphorylation >> Ser / Thr Kinases >> MAPK Pathway
Epigenetics and Nuclear Signaling >> DNA / RNA >> DNA Damage & Repair >> DNA Damage Response >> Other
Cell Biology >> Apoptosis >> Intracellular >> Associated Proteins

  • SDS-PAGE - GADD45B protein (Human) (ab79246)SDS-PAGE - GADD45B protein (Human) (ab79246) image (enlarge)

Applications

Show applications key

Our Abpromise guarantee covers the use of ab79246 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Protein info

Function

Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.

Sequence similarities

Belongs to the GADD45 family.

Target information above from: UniProt accessionO75293 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).

Information by UniProt

GADD45B protein (Human) images:

  SDS-PAGE - GADD45B protein (Human) (ab79246)

SDS-PAGE - GADD45B protein (Human) (ab79246)

15% SDS-PAGE showing ab79246 at approximately 18kDa (3µg).

References for GADD45B protein (Human) (ab79246)

ab79246 has not yet been referenced specifically in any publications.

Publishing research using ab79246? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"