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Western blot - GADD45GIP1 antibody (ab73111)
(enlarge)
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Product Name
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GADD45GIP1 antibody
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See all GADD45GIP1 antibodies (2)...
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Product type
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Primary antibodies
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Description
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Mouse polyclonal to GADD45GIP1
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Immunogen
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Full length protein, corresponding to amino acids 1-222 of Human GADD45GIP1 (NP_443082)
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at an assay dependent dilution. Predicted molecular weight: 25 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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Transfected 293T cell lysate
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Cellular localization
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Nuclear
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Research areas
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Cancer >> Oncoproteins/suppressors >> Tumor suppressors >> Other
Chromatin and Nuclear Signaling >> Nuclear Signaling Pathways >> Nuclear Receptors >> Co-activators/co-repressors
Signal Transduction >> Signaling Pathway >> Nuclear Signaling >> Nuclear Hormone Receptors >> Co-activators/co-repressors
Cell Biology >> Cell Cycle >> Cell Cycle Inhibitors >> Other
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Relevance
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Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain mediated transcriptional activity. May be involved in the hormone mediated regulation of NR4A1 transcriptional activity.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Whole antiserum
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Storage buffer
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Preservative: None
Constituents: Whole serum
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Form
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Liquid
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Concentration
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Concentration not determined - why is this?
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Storage instructions
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Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GADD45GIP1 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for GADD45GIP1 antibody images, references, products related to ab73111 and other tools.
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GADD45GIP1 antibody images:
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 Western blot - GADD45GIP1 antibody (ab73111)
All lanes : GADD45GIP1 antibody (ab73111) at 1/500 dilution
Lane 1 : GADD45GIP1-transfected 293T cell lysate (24.42 KDa)
Lane 2 : non-transfected 293T cell lysate
Lysates/proteins at 25 µg per lane.
Secondary
HRP-conjugated goat anti-mouse at 1/2500 dilution
Predicted band size : 25 kDa
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Search PubMed (MEDLINE) for references to GADD45GIP1
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GADD45GIP1 antibody - more information
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Customer reviews (feedback) regarding GADD45GIP1 antibody |
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GADD45GIP1 antibody - related products:
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GADD45GIP1 antibody - other tools:
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