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Overview
Product name
Anti-GAS41 antibody - N-terminal
See all GAS41 products (2) ...
Description
Rabbit polyclonal to GAS41 - N-terminal
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Immunogen
Synthetic peptide from the N-terminal region of human GAS41 conjugated to KLH
Positive control
HepG2 cell line lysate.
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.09% Sodium Azide
Constituents: PBS
Concentration
Concentration information loading...
Purity
Ammonium Sulphate Precipitation
Purification notes
ab71260 is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Clonality
Polyclonal
Isotype
IgG
-
Western blot - GAS41 antibody - N-terminal (ab71260)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab71260 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
ELISA: 1/1000ELISA: 1/1000
WB: 1/100 - 1/500.Detects a band of approximately 30 kDa (predicted molecular weight: 27 kDa).
Target
Function
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Tissue specificity
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Sequence similarities
Contains 1 YEATS domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionO95619
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 4930573H17Rik antibody
- B230215M10Rik antibody
- GAS 41 antibody
see all
Database links
- Entrez Gene: 8089 Human
- Omim: 602116 Human
- SwissProt: O95619 Human
- Unigene: 4029 Human
Anti-GAS41 antibody - N-terminal images:
Western blot - GAS41 antibody - N-terminal (ab71260)
Anti-GAS41 antibody - N-terminal (ab71260) at 1/100 dilution + HepG2 cell line lysate at 12.5 µg
Predicted band size : 27 kDa
Observed band size : 30 kDa (why is the actual band size different from the predicted?)
Additional bands at : 45 kDa. We are unsure as to the identity of these extra bands.
References for Anti-GAS41 antibody - N-terminal (ab71260)
ab71260 has not yet been referenced specifically in any publications.
Publishing research using ab71260? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"