![Western blot - GAS41 antibody [YEATB1A8] (ab50963) image](#ab50963_wb1.jpg)
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Overview
Product name
Anti-GAS41 antibody [YEATB1A8]
See all GAS41 products (2) ...
Description
Mouse monoclonal [YEATB1A8] to GAS41
Tested applications
WB, Dot Blotmore details
Cross reactivity
Reacts with
Human
Immunogen
Recombinant human YEATS4 fragment
Properties
Form
Liquid
Storage instructions
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.05% Sodium Azide
Constituents: 1% BSA, PBS, 3mM Potassium chloride, 140mM Sodium chloride, 1.5mM KH2PO4, 8.0mM Na2HPO4, pH 7.4
Concentration
Concentration information loading...
Purity
Protein G purified
Purification notes
ab50963 was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
Clonality
Monoclonal
Clone number
YEATB1A8
Isotype
IgG1
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Western blot - GAS41 antibody [YEATB1A8] (ab50963)
![Western blot - GAS41 antibody [YEATB1A8] (ab50963) image](/ps/datasheet/Images/50/ab50963/ab50963_wb1.jpg)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab50963 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
WB: Use at an assay dependent dilution. Predicted molecular weight: 27 kDa.
Dot: Use at an assay dependent dilution.
Target
Function
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Tissue specificity
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Sequence similarities
Contains 1 YEATS domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionO95619
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- 4930573H17Rik antibody
- B230215M10Rik antibody
- GAS 41 antibody
see all
Database links
- Entrez Gene: 8089 Human
- Omim: 602116 Human
- SwissProt: O95619 Human
- Unigene: 4029 Human
Anti-GAS41 antibody [YEATB1A8] images:
Western blot - GAS41 antibody [YEATB1A8] (ab50963)
Anti-GAS41 antibody [YEATB1A8] (ab50963) + Immunized recombinant YEATS4
Predicted band size : 27 kDa
Observed band size : 32 kDa (why is the actual band size different from the predicted?)
References for Anti-GAS41 antibody [YEATB1A8] (ab50963)
ab50963 has not yet been referenced specifically in any publications.
Publishing research using ab50963? Please let us know so that we can cite the reference in this datasheet
![GAS41 antibody [YEATB1A8] for Western blot in Mouse (50963)](/ps/datasheet/images/50/ab50963/GAS41-Primary-antibodies-ab50963-6.jpg)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"