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Overview
Product name
GAS41 protein (T7 Tag)
See all GAS41 products (2) ...
Protein description
Recombinant full length protein (Human) fused to T7 tag at N-terminal end.
Expression host
E. coli
Properties
Purity
>90% by SDS-PAGE
Form
Liquid
Storage instructions
Aliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.002% Sodium Azide
Constituents: 0.1% Triton-X-100, 10mM Tris, pH 8.0
Concentration
Concentration information loading...
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SDS-PAGE - GAS41 protein (ab40052)
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Applications
Show applications key
Our Abpromise guarantee covers the use of ab40052 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
SDS-PAGE: Use at an assay dependent dilution.
MS: Use at an assay dependent dilution.
Protein info
Function
Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when recruited to sites of DNA damage.
Tissue specificity
Expressed in brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle.
Sequence similarities
Contains 1 YEATS domain.
Cellular localization
Nucleus.
Target information above from: UniProt accessionO95619
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
GAS41 protein (T7 Tag) images:
SDS-PAGE - GAS41 protein (ab40052)
SDS-PAGE analysis of GAS41 protein.
4-20% SDS gradient gel.
Coomassie blue staining.
References for GAS41 protein (T7 Tag) (ab40052)
ab40052 has not yet been referenced specifically in any publications.
Publishing research using ab40052? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"