Anti-GCKR antibody (ab65224)

Overview

• Product nameAnti-GCKR antibodySee all GCKR primary antibodies ...
• Description
  Rabbit polyclonal to GCKR
• Specificityab65224 detects endogenous levels of total GCKR protein.
• Tested applicationsELISA, WB more details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  
• Immunogen

  Synthetic peptide derived from an internal sequence of human GCKR

• Positive controlMouse heart and rat heart cell extracts

Properties

• FormLiquid
• Storage instructionsStore at -20°C. Stable for 12 months at -20°C
• Storage bufferPreservative: 0.02% Sodium Azide
  Constituents: 50% Glycerol, PBS (without Mg²⁺ and Ca²⁺), 150mM Sodium chloride, pH 7.4
• Concentration information loading...
• PurityImmunogen affinity purified
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Heart disease

  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Types of disease
  • Diabetes

  • Metabolism
  • Types of disease
  • Metabolic disorders

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Carbohydrate metabolism

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Energy Metabolism

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Metabolism of carbohydrates

  • Signal Transduction
  • Metabolism
  • Energy Metabolism

  • Cardiovascular
  • Atherosclerosis
  • Diabetes associated

Applications

Target

• FunctionInhibits glucokinase by forming an inactive complex with this enzyme.
• Tissue specificityFound in liver and pancreas. Not detected in muscle, brain, heart, thymus, intestine, uterus, adipose tissue, kidney, adrenal, lung or spleen.
• Sequence similaritiesBelongs to the GCKR family.
  Contains 2 SIS domains.

Target information above from: UniProt accession Q14397 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 2646 Human
  • Entrez Gene: 231103 Mouse
  • Entrez Gene: 25658 Rat
  • Omim: 600842 Human
  • SwissProt: Q14397 Human
  • SwissProt: Q91X44 Mouse
  • SwissProt: Q07071 Rat
  • Unigene: 89771 Human

  • Unigene: 100043 Mouse
  • Unigene: 7863 Rat

  see all

• Alternative names
  FGQTL5 antibodyGCK antibodyGCKR antibody

  GCKR_HUMAN antibodyGKRP antibodyGLRE antibodyglucokinase (hexokinase 4) regulator antibodyGlucokinase antibodyGlucokinase regulator antibodyGlucokinase regulatory protein antibodyHexokinase type IV antibodyHexokinase-4 antibodyHexokinase-D antibodyHK IV antibodyHK4 antibodyOTTHUMP00000158533 antibody

  see all

Anti-GCKR antibody images

• 

  Western blot - GCKR antibody (ab65224)
  All lanes : Anti-GCKR antibody (ab65224) at 1/500 dilution
  
  Lane 1 : mouse heart cell extract
  Lane 2 : rat heart cell extract
  Lane 3 : rat heart cell extract with immunising peptide
  
  
  Predicted band size : 69 kDa
  Observed band size : 69 kDa