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Western blot - GCLC antibody (ab41463)
(enlarge)
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Product Name
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GCLC antibody
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See all GCLC antibodies (6)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to GCLC
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Immunogen
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Synthetic peptide conjugated to KLH derived from within residues 50 - 150 of Human GCLC. (Peptide available as ab41462.)
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cow
(Due to sequence homology)
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1 µg/ml. Detects a band of approximately 73 kDa (predicted molecular weight: 73 kDa).
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Positive control
(see definition)
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This antibody gave a positive signal in the following Human Tissue Lysates: Liver, Kidney and Lung (Adenocarcinoma).
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Cellular localization
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Cytoplasmic
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Research areas
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Cell Biology >> Other Antibodies >> Other Antibodies
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Mitochondrial
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Relevance
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Gamma-glutamylcysteine synthetase catalyses the first step in the synthesis of glutathione. The enzyme is composed of a 73 kDa heavy chain and a smaller regulatory sub-unit. Defects in GCLC are the cause of hemolytic anemia.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Immunogen affinity purified
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS, pH 7.4 Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.800 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GCLC antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for GCLC antibody images, references, products related to ab41463 and other tools.
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GCLC antibody images:
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Search PubMed (MEDLINE) for references to GCLC
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GCLC antibody - more information
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Customer reviews (feedback) regarding GCLC antibody |
Customer FAQs regarding GCLC antibody |
Protocols for GCLC antibody |
Price and availability of products related to GCLC antibody |
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GCLC antibody - related products:
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GCLC antibody - other tools:
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Contact Abcam with a Technical Enquiry about GCLC antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
Pricing information loading
Western blot - GCLC antibody (ab41463)