Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate
Overview
Product name
Anti-GCLM antibody
See all GCLM products (3) ...
Description
Mouse monoclonal to GCLM
Tested applications
Cross reactivity
Reacts with
Human
Immunogen
Recombinant full length protein, corresponding to amino acids 1-275 of Human GCLM (Gamma Glutamylcysteine Synthetase regulatory subunit).
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: None
PBS, pH 7.2
Concentration
Concentration information loading...
Purity
Protein G purified
Clonality
Monoclonal
Isotype
IgG2a
Light chain type
kappa
Research areas
Cell Biology >> Other Antibodies >> Other Antibodies
Cell Biology >> Other Antibodies >> Oxidative Stress
Signal Transduction >> Metabolism >> Drug metabolism
Signal Transduction >> Metabolism >> Mitochondrial
Signal Transduction >> Metabolism >> Energy Metabolism
Signal Transduction >> Metabolism >> Amino Acids
Neuroscience >> Neurotransmitter >> Amino Acids >> Glutamate
-
Western blot - GCLM antibody (ab55436)
(enlarge)
Applications
Show applications key
Our Abpromise guarantee covers the use of ab55436 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 1 Image
WB
Application notes
WB: Use at a concentration of 1-5 µg/ml.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Tissue specificity
In all tissues examined. Highest levels in skeletal muscle.
Pathway
Sulfur metabolism; glutathione biosynthesis; glutathione from L-cysteine and L-glutamate: step 1/2.
Sequence similarities
Belongs to the aldo/keto reductase family. Glutamate--cysteine ligase light chain subfamily.
Target information above from: UniProt accessionP48507
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- Gamma ECS regulatory subunit antibody
- Gamma-ECS regulatory subunit antibody
- Gamma-glutamylcysteine synthetase regulatory subunit antibody
see all
Database links
- Entrez Gene: 2730 Human
- SwissProt: P48507 Human
- Unigene: 315562 Human
Anti-GCLM antibody images:
Western blot - GCLM antibody (ab55436)
Predicted band size : 31 kDa
GCLM (ab55436) at 1ug/lane + HeLa cell lysate at 25ug/lane.
References for Anti-GCLM antibody (ab55436)
This product has been referenced in:
- Jackson RM & Gupta C Hypoxia and kinase activity regulate lung epithelial cell glutathione. Exp Lung Res 36:45-56 (2010).Read more (PubMed: 20128681) »
See 1 publication for this product
Publishing research using ab55436? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"