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Overview

  • Product nameGDF15 proteinSee all GDF15 proteins and peptides ...
  • Protein descriptionNative protein (purified): ARNGDHCPLG PGRCCRLHTV RASLEDLGWA DWVLSPREVQ VTMCIGACPS QFRAANMHAQ IKTSLHRLKP DTVPAPCCVP ASYNPMVLIQ KTDTGVSLQT YDDLLAKDCH CI (Human)
  • Expression hostCell Culture

    • Properties

  • Purity> 98 % by SDS-PAGE
  • Purification notesab50077 purity was determined also by HPLC Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised:Reconstitute to 1mg/ml with distilled water.
  • Storage instructionsThe lyophilized protein is stable for a few weeks at room temperature, but best stored at -20°C.
  • Concentration information loading...
  • SequenceARNGDHCPLGPGRCCRLHTVRASLEDLGWADWVLSPREVQ VTMCIGACPSQFRAANMHAQIKTSLHRLKPDTVPAPCCVP ASYNPMVLIQKTDTGVSLQTYDDLLAKDCHCI
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab50077 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        GDF 15GDF-15Gdf15
        GDF15_HUMANGrowth differentiation factor 15Growth/differentiation factor 15Macrophage inhibitory cytokine 1MIC 1Mic-1MIC1NAG 1NAG-1NAG1NRG 1NRG-1NRG1NSAIDNSAID (nonsteroidal anti inflammatory drug) activated protein 1NSAID regulated protein 1NSAID-activated gene 1 proteinNSAID-regulated gene 1 proteinPDFPLABPlacental bone morphogenetic proteinPlacental bone morphogenic proteinPlacental TGF betaPlacental TGF-betaProstate differentiation factorPTGF betaPTGFB
      see all
  • Tissue specificityHighly expressed in placenta, with lower levels in prostate and colon and some expression in kidney.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession Q99988 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for GDF15 protein (ab50077)

    ab50077 has not yet been referenced specifically in any publications.

    Publishing research using ab50077 ? Please let us know so that we can cite the reference in this datasheet

    Product Wall

    Submit an Abreview for ab50077 Submit a Question for ab50077

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    Cusotmer kindly contacted us to discuss GDF15 proteins. What was the original buffer in which this product was lyophilized in? While re-suspention in water, will the solution be of neutral pH?

    Thank you for contacting us.

    I have recieved from the lab further information about ab50077 GDF15 protein. This product was was lyophilized from 10 mM Sodium Citrate, pH 3.0.

    I hope this information is helpful to you. Please do n...

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    I have a question on one of your products. It is a human GDF15, Cat. No. ab50077. Is this a recombinant protein or native protein produced by a certain human cell line expressing hGDF15 endogenously? I’m happy if you could answer.

    Thank you very much for contacting us with your question.

    I can confirm that the GDF15 protein ab50077 is naturally secreted by a proprietary cell line and then purified. No recombinant techniques are involved in the production of this protein. ...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"