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GDF8 / Myostatin protein (Propeptide domain) (ab63300)

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Overview

  • Product nameGDF8 / Myostatin protein (Propeptide domain)See all GDF8 / Myostatin proteins and peptides ...
  • Protein descriptionRecombinant fragment, corresponding to Propeptide domain, amino acids 24-266 of Human GDF8 / Myostatin, Swiss_Prot O14793. 243 amino acids with 5 extra residues, calculated MW 28kDa.
  • Expression hostE. coli

    • Properties

  • Purity> 95 % by SDS-PAGE
  • FormLiquid
  • Storage instructionsAliquot and store at -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 20mM Sodium chloride, 20mM Tris, pH 8
  • Concentration information loading...
  • Additional notesProduct is NOT sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.
  • Sequence notes MG NENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRR KLN
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab63300 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    WB WB: Use at an assay dependent dilution. Predicted molecular weight: 28 kDa.
    ELISA ELISA: Use at an assay dependent dilution.

    Protein info

    • Alternative names
        GDF 8GDF-8GDF8_HUMAN
        Growth differentiation factor 8Growth/Differentiation Factor 8MSTNmyostatinOTTHUMP00000163498
      see all
  • FunctionActs specifically as a negative regulator of skeletal muscle growth.
  • Sequence similaritiesBelongs to the TGF-beta family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession O14793 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    GDF8 / Myostatin protein (Propeptide domain) images

    • SDS-PAGE - GDF8 / Myostatin protein (Propeptide domain) (ab63300)
      SDS-PAGE - GDF8 / Myostatin protein (Propeptide domain) (ab63300)
      LANES:
      1. MW marker – 14, 21, 31, 45, 66, 97 kDa
      2. reduced and heated sample, 7µg/lane
      3. non-reduced and non-heated sample, 7µg/lane

    References for GDF8 / Myostatin protein (Propeptide domain) (ab63300)

    ab63300 has not yet been referenced specifically in any publications.

    Publishing research using ab63300 ? Please let us know so that we can cite the reference in this datasheet

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