Loading...
You have changed your country from
to
. Please be aware that this will change the currency in the purchasing process.
Products:Neuroscience >> Neurology process >> Growth and Development >> Neurotrophins
Overview
Product name
GFR alpha 3 peptide
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.1% BSA, PBS, pH 7.2
Concentration
Concentration information loading...
Additional notes
Stable for one year.
Sequence notes
RFHRQLFSQD WADS Amin o acids 347-360 of murine GFR alpha 3
Research areas
Neuroscience >> Neurology process >> Growth and Development >> Neurotrophins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab6100 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
BL: Use at an assay dependent dilution. (Incubation with an equal volume of antibody for 30 minutes at 37°C will usually completely block the antibody activity.)
Application notes
This peptide can be used with studies using ab8028.
Protein info
Function
Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase.
Tissue specificity
Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression. Very low or no expression detected in the hematopoietic system.
Sequence similarities
Belongs to the GDNFR family.
Post-translational
modifications
N-glycosylated.
Cellular localization
Cell membrane.
Target information above from: UniProt accessionO60609
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
References for GFR alpha 3 peptide (ab6100)
ab6100 has not yet been referenced specifically in any publications.
Publishing research using ab6100? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"