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Overview

  • Product nameGGPS1 proteinSee all GGPS1 proteins and peptides ...
  • Protein descriptionRecombinant full length Human GGPS1 (amino acids 1-300) with N terminal His tag; 320 amino acids with tag; Predicted MWt 37 kDa (NP_001032354).
  • Uniprot accessionO95749
  • Molecular weight37kDa inclusive of tags
  • Protein length300 amino acids
  • Expression hostE. coli

    • Properties

  • Purity> 90 % by SDS-PAGE
  • Purification notesab100959 was purified using conventional chromatography techniques.
  • Mass spectrometryMALDI-TOF
  • E.C. Number2.5.1.1
  • FormLiquid
  • Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • Storage bufferPreservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0
  • Concentration information loading...
  • SequenceMGSSHHHHHHSSGLVPRGSHMEKTQETVQRILLEPYKYLL QLPGKQVRTKLSQAFNHWLKVPEDKLQIIIEVTEMLHNAS LLIDDIEDNSKLRRGFPVAHSIYGIPSVINSANYVYFLGL EKVLTLDHPDAVKLFTRQLLELHQGQGLDIYWRDNYTCPT EEEYKAMVLQKTGGLFGLAVGLMQLFSDYKEDLKPLLNTL GLFFQIRDDYANLHSKEYSENKSFCEDLTEGKFSFPTIHA IWSRPESTQVQNILRQRTENIDIKKYCVHYLEDVGSFEYT RNTLKELEAKAYKQIDARGGNPELVALVKHLSKMFKEENE
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab100959 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    MS MS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab151696,ab155584 and ab167168.

    • Protein info

    • Alternative names
        (2E6E)-farnesyl diphosphate synthaseDimethylallyltranstransferase
        Farnesyl diphosphate synthaseFarnesyltranstransferaseGeranylgeranyl diphosphate synthaseGeranylgeranyl diphosphate synthase 1Geranylgeranyl pyrophosphate synthaseGeranylgeranyl pyrophosphate synthetaseGeranyltranstransferaseGGPP synthaseGGPP synthetaseGGPPSGGPPS_HUMANGGPPS1GGPPSaseGGPS1OTTHUMP00000036073OTTHUMP00000216161OTTHUMP00000216163OTTHUMP00000216164
      see all
  • FunctionCatalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins.
  • Tissue specificityAbundantly expressed in testis. Found in other tissues to a lower extent.
  • PathwayIsoprenoid biosynthesis; farnesyl diphosphate biosynthesis; farnesyl diphosphate from geranyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranyl diphosphate biosynthesis; geranyl diphosphate from dimethylallyl diphosphate and isopentenyl diphosphate: step 1/1.
    Isoprenoid biosynthesis; geranylgeranyl diphosphate biosynthesis; geranylgeranyl diphosphate from farnesyl diphosphate and isopentenyl diphosphate: step 1/1.
  • Sequence similaritiesBelongs to the FPP/GGPP synthase family.
  • Cellular localizationCytoplasm.

    • Target information above from: UniProt accession O95749 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    GGPS1 protein images

    • SDS-PAGE - GGPS1 protein (ab100959)
      SDS-PAGE - GGPS1 protein (ab100959)
      15% SDS-PAGE showing ab100959 at approximately 37kDa (3µg).

    References for GGPS1 protein (ab100959)

    ab100959 has not yet been referenced specifically in any publications.

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