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Product Name
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GIP antibody (Biotin)
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See all GIP antibodies (4)...
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Product type
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Primary antibodies
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Description
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Rabbit polyclonal to GIP (Biotin)
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Immunogen
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Synthetic peptide: YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQ conjugated to KLH via carboxyl group, corresponding to internal sequence amino acids 52-93 of Human GIP.
BLAST 'YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI ' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Rat, Cow, Pig
(Due to sequence homology)
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Tested applications
(see key)
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ELISA, IP, RIA
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ELISA: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
RIA: Use at an assay dependent dilution.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Secreted
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Research areas
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Signal Transduction >> Growth Factors/Hormones >> Hormones
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR
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Relevance
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Gastric inhibitory peptide, GIP, is a 42 amino acid residue protein and is principally produced in K cells in the duodenum, jejunum and, occasionally, upper ileum. GIP may also be expressed in non intestinal tissues such as rat salivary glands. It is a potent stimulator of insulin secretion in hyperglycemia. GIP acts by binding to specific G protein coupled receptors on the pancreatic islet cell membrane. An internal domain of GIP may be responsible and that the mechanism of ligand activated signal transduction is via a wortmannin sensitive pathway.
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GIP antibody (Biotin) (ab48286) |
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Rabbit
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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Protein G purified
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Storage buffer
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Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5 Material safety datasheets (MSDS) for this product:
Glycerol MSDS
Thimerosal MSDS
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Form
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Liquid
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Conjugation
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Biotin
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Concentration
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Batch dependent within range: 0.22 - 0.22 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GIP antibody (Biotin) is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to GIP
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GIP antibody (Biotin) - more information
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Customer reviews (feedback) regarding GIP antibody (Biotin) |
Customer FAQs regarding GIP antibody (Biotin) |
Protocols for GIP antibody (Biotin) |
Price and availability of products related to GIP antibody (Biotin) |
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GIP antibody (Biotin) - related products:
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GIP antibody (Biotin) - other tools:
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Contact Abcam with a Technical Enquiry about GIP antibody (Biotin) |
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