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Anti-GIP antibody (Biotin) (ab48286)

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Overview

Product name

Anti-GIP antibody (Biotin)
See all GIP products (4) ...

Description

Rabbit polyclonal to GIP (Biotin)

Conjugation

Biotin

Tested applications

ELISA, IP, RIAmore details

Cross reactivity

Reacts with

Human

Predicted to work with

Mouse, Rat, Cow, Pig

Immunogen

Synthetic peptide: YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQ conjugated to KLH via carboxyl group, corresponding to internal sequence amino acids 52-93 of Human GIP.

YAEGTFISDY SIAMDKIHQQ DFVNWLLAQK GKKNDWKHNI TQ

Run BLAST with BLAST the sequence with ExPASyRun BLAST with BLAST the sequence with NCBI

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Storage buffer

Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 50% Glycerol, PBS, pH 7.5

Concentration

Concentration information loading...

Purity

Protein G purified

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Growth Factors/Hormones >> Hormones
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR

Applications

Show applications key

Our Abpromise guarantee covers the use of ab48286 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Target

Relevance

Gastric inhibitory peptide, GIP, is a 42 amino acid residue protein and is principally produced in K cells in the duodenum, jejunum and, occasionally, upper ileum. GIP may also be expressed in non intestinal tissues such as rat salivary glands. It is a potent stimulator of insulin secretion in hyperglycemia. GIP acts by binding to specific G protein coupled receptors on the pancreatic islet cell membrane. An internal domain of GIP may be responsible and that the mechanism of ligand activated signal transduction is via a wortmannin sensitive pathway.

Cellular localization

Secreted

Alternative names

  • Gastric Inhibitory Peptide antibody
  • Gastric inhibitory polypeptide precursor antibody
  • GIP antibody
  • Glucose dependent insulinotropic polypeptide antibody

Database links

see all

References for Anti-GIP antibody (Biotin) (ab48286)

ab48286 has not yet been referenced specifically in any publications.

Publishing research using ab48286? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"