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Anti-GIP antibody (ab22624)

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Overview

Product name

Anti-GIP antibody
See all GIP products (4) ...

Description

Rabbit polyclonal to GIP

Specificity

ab22624 reacts with Glucose-dependent Insulinotropic Peptide (GIP).

Tested applications

IHC-P, IHC-R, Flow Cytmore details

Cross reactivity

Reacts with

Mouse, Pig

Immunogen

Full length native protein (purified) (Pig) conjugated to KLH by a CDI linker.

Positive control

Mammalian duodenal (K) endocrine cells.

Properties

Form

Liquid

Storage instructions

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Storage buffer

Preservative: 0.1% Sodium Azide
Constituents: Whole serum

Purity

Whole antiserum

Clonality

Polyclonal

Isotype

IgG

Research areas

Signal Transduction >> Growth Factors/Hormones >> Hormones
Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> GPCR

Applications

Show applications key

Our Abpromise guarantee covers the use of ab22624 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • ShowHide

    IHC-P

     IHC-P: 1/1000 - 1/8000.(...Read more →

    IHC-P: 1/1000 - 1/8000.(1/1000 - 1/8000 (using method A) and 1/200-1/1200 (using method B) Dilute to working strength with phosphatebuffered saline (PBS) containing 0.1% w/v sodium azide. Method A: using overnight incubation and indirect immunoperoxidase procedures, such as PAP and ABCperoxidase. Method B: using overnight incubation and indirect immunofluorescence procedures.)

  • ShowHide

    IHC-R

     IHC-R: 1/1000 - 1/8000.(...Read more →

    IHC-R: 1/1000 - 1/8000.(1/1000 - 1/8000 (using method A) and 1/200-1/1200 (using method B) Dilute to working strength with phosphatebuffered saline (PBS) containing 0.1% w/v sodium azide. Method A: using overnight incubation and indirect immunoperoxidase procedures, such as PAP and ABCperoxidase. Method B: using overnight incubation and indirect immunofluorescence procedures.)

  • Flow Cyt

    Four stars (1 Abreview) Flow Cyt: 1/150

    Flow Cyt: 1/150

Target

Relevance

Gastric inhibitory peptide, GIP, is a 42 amino acid residue protein and is principally produced in K cells in the duodenum, jejunum and, occasionally, upper ileum. GIP may also be expressed in non intestinal tissues such as rat salivary glands. It is a potent stimulator of insulin secretion in hyperglycemia. GIP acts by binding to specific G protein coupled receptors on the pancreatic islet cell membrane. An internal domain of GIP may be responsible and that the mechanism of ligand activated signal transduction is via a wortmannin sensitive pathway.

Cellular localization

Secreted

Alternative names

  • Gastric Inhibitory Peptide antibody
  • Gastric inhibitory polypeptide antibody
  • Gastric inhibitory polypeptide precursor antibody
  • GIP antibody
  • Glucose dependent insulinotropic polypeptide antibody
  • Glucose-dependent insulinotropic polypeptide antibody
see all

Database links

References for Anti-GIP antibody (ab22624)

ab22624 has not yet been referenced specifically in any publications.

Publishing research using ab22624? Please let us know so that we can cite the reference in this datasheet

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"