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Overview

  • Product nameGM-CSF protein (Active)See all GM-CSF proteins and peptides ...
  • Protein descriptionHighly pure (>98%) recombinant mouse GM-CSF.
  • Expression hostE. coli

    • Properties

  • Purification notesSterile filtered Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • FormLyophilised
  • Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.This product is an active protein and may elicit a biological response in vivo, handle with caution.
  • Concentration information loading...
  • Additional notesThe ED50, determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells, is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 107 units/mg.
  • Sequence notesRecombinant Murine GM-CSF is a 14.2 kDa protein containing 124 amino acid residues: MAPTRSPITV TRPWKHVEAI KEALN LLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIFEQ GLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVT T YADFIDSLKT FLTDIPFECKKPVQK
  • Research Areas

    • Applications

    Our Abpromise guarantee covers the use of ab9742 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Notes
    Functional Studies FuncS: Use at an assay dependent dilution.
    SDS-PAGE SDS-PAGE: Use at an assay dependent dilution.
  • Application notesThis peptide can be used with studies using ab9741,ab18636,ab18643 and ab18655.

    • Protein info

    • Alternative names
        Burst Promoting ActivityCMCSFColony stimulating factor
        Colony Stimulating Factor 2Colony stimulating factor 2 (granulocyte-macrophage)Colony-stimulating factorCSFCSF 2CSF AlphaCSF2CSF2_HUMANEosinophil Colony Stimulating FactorGM-CSFGMCSFGranulocyte Macrophage Colony Stimulating FactorGranulocyte-macrophage colony-stimulating factorMGC131935MGC138897MolgramostinPluripoietin AlphaSargramostim
      see all
  • FunctionCytokine that stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
  • Sequence similaritiesBelongs to the GM-CSF family.
  • Cellular localizationSecreted.

    • Target information above from: UniProt accession P04141 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

    References for GM-CSF protein (Active) (ab9742)

    ab9742 has not yet been referenced specifically in any publications.

    Publishing research using ab9742 ? Please let us know so that we can cite the reference in this datasheet

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