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Overview

  • Product nameAnti-GNAI3 antibodySee all GNAI3 primary antibodies ...
  • Description
    Rabbit polyclonal to GNAI3
  • Tested applicationsWB more details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to a region within N-terminal amino acids 43-92 (ESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSI IAIIRAMGRLK) of Human GNAI3 (NP_006487).

    Run BLAST with BLAST the sequence with ExPASy Run BLAST with BLAST the sequence with NCBI
  • Positive controlFetal Brain Lysate

Properties

Applications

Our Abpromise guarantee covers the use of ab108172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Notes
WB WB: Use a concentration of 1 µg/ml. Predicted molecular weight: 41 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

Target

  • FunctionGuanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor-regulated K(+) channels. The active GTP-bound form prevents the association of RGS14 with centrosomes and is required for the translocation of RGS14 from the cytoplasm to the plasma membrane. May play a role in cell division.
  • Sequence similaritiesBelongs to the G-alpha family. G(i/o/t/z) subfamily.
  • Cellular localizationCytoplasm. Cell membrane. Cytoplasm > cytoskeleton > centrosome. Localizes in the centrosomes of interphase and mitotic cells. Detected at the cleavage furrow and/or the midbody.

    • Target information above from: UniProt accession P08754 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Database links
    • Alternative names
        87U6 antibodyFLJ26559 antibodyG protein alpha inhibiting 3 antibody
        G(i) alpha 3 antibodyG(i) alpha-3 antibodyGNAI3 antibodyGNAI3_HUMAN antibodyGuanine nucleotide binding protein (G protein) alpha inhibiting activity polypeptide 3 antibodyGuanine nucleotide binding protein G(k) alpha subunit antibodyGuanine nucleotide-binding protein G(k) subunit alpha antibodyOTTHUMP00000013368 antibody
      see all

    Anti-GNAI3 antibody images

    • Western blot - GNAI3 antibody (ab108172)
      Western blot - GNAI3 antibody (ab108172)
      Anti-GNAI3 antibody (ab108172) at 1 µg/ml + Fetal Brain Lysate at 10 µg

      Predicted band size : 41 kDa

    References for Anti-GNAI3 antibody (ab108172)

    ab108172 has not yet been referenced specifically in any publications.

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