Anti-GNB1 antibody (ab72484)

Overview

• Product nameAnti-GNB1 antibodySee all GNB1 primary antibodies ...
• Description
  Rabbit polyclonal to GNB1
• Tested applicationsWB, IHC-P, IHC-Fr more details
• Species reactivity
  Reacts with: Mouse, Rat, Human
  Predicted to work with: Xenopus laevis, Zebrafish
• Immunogen

  A synthetic peptide from the internal part of human GNB1 conjugated to an immunogenic carrier protein. The peptide is homologous in many species including rat, mouse, zebrafish and xenopus.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50%, aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: Whole serum
• PurityWhole antiserum
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Metabolism
  • Types of disease
  • Cancer

  • Metabolism
  • Pathways and Processes
  • Metabolic signaling pathways
  • Energy transfer pathways
  • Integration of energy

  • Cancer
  • Cancer Metabolism
  • Metabolic signaling pathway
  • Integration of energy metabolism

  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • Heterotrimeric G Proteins
  • G Proteins

Applications

Target

• FunctionGuanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
• Sequence similaritiesBelongs to the WD repeat G protein beta family.
  Contains 7 WD repeats.
• Post-translational
  modificationsPhosphorylation at His-266 by NDKB contributes to G protein activation by increasing the high energetic phosphate transfer onto GDP.

Target information above from: UniProt accession P62873 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 2782 Human
  • Entrez Gene: 14688 Mouse
  • Entrez Gene: 24400 Rat
  • Entrez Gene: 322104 Zebrafish
  • Omim: 139380 Human
  • SwissProt: P62873 Human
  • SwissProt: P62874 Mouse
  • SwissProt: P54311 Rat

  • SwissProt: P79959 Xenopus laevis
  • SwissProt: Q6PH57 Zebrafish
  • Unigene: 430425 Human
  • Unigene: 2344 Mouse
  • Unigene: 126047 Rat
  • Unigene: 4840 Xenopus laevis
  • Unigene: 134498 Zebrafish

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• Alternative names
  Beta subunit signal transducing proteins GS/GI antibodyG protein beta 1 subunit antibodyGBB1 antibody

  GBB1_HUMAN antibodygnb1 antibodyGuanine nucleotide binding protein (G protein) beta polypeptide 1 antibodyGuanine nucleotide binding protein beta 1 subunit antibodyGuanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 antibodyTransducin beta chain 1 antibody

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