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Products:Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Heterotrimeric G Proteins >> G Proteins
Overview
Product name
Anti-GNB3 antibody
See all GNB3 products (6) ...
Description
Goat polyclonal to GNB3
Specificity
No cross-reactivity expected with GNB1, 2 and 4
Tested applications
ELISA, WBmore details
Cross reactivity
Reacts with
Human
Predicted to work with
Xenopus laevis, Zebrafish
Immunogen
Synthetic peptide: DCMSLAVSPDFN, corresponding to internal sequence amino acids 186-197 of Human GNB3
DCMSLAVSPD FN
Properties
Form
Liquid
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage buffer
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
Concentration
Concentration information loading...
Purity
Immunogen affinity purified
Purification notes
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Clonality
Polyclonal
Isotype
IgG
Research areas
Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Cardiovascular >> Blood >> Blood Pressure regulation
Neuroscience >> Sensory System >> Taste system
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Heterotrimeric G Proteins >> G Proteins
Applications
Show applications key
Our Abpromise guarantee covers the use of ab48007 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ELISA
WB
Application notes
ELISA: Use at an assay dependent dilution. Antibody detection limit dilution 1:1,000
WB: Use at an assay dependent concentration. Predicted molecular weight: 37 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Target
Function
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
Sequence similarities
Belongs to the WD repeat G protein beta family.
Contains 7 WD repeats.
Target information above from: UniProt accessionP16520
The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010).
Alternative names
- G protein beta 3 subunit antibody
- GBB3_HUMAN antibody
- GNB3 antibody
see all
Database links
- Entrez Gene: 2784 Human
- Entrez Gene: 380378 Xenopus laevis
- Entrez Gene: 406483 Zebrafish
- Omim: 139130 Human
- SwissProt: P16520 Human
- Unigene: 631657 Human
References for Anti-GNB3 antibody (ab48007)
ab48007 has not yet been referenced specifically in any publications.
Publishing research using ab48007? Please let us know so that we can cite the reference in this datasheet
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"