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Western blot - GNB3 antibody (ab55121)
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Immunocytochemistry/ Immunofluorescence-GNB3 antibody(ab55121)
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Product Name
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GNB3 antibody
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See all GNB3 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to GNB3
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Immunogen
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Recombinant full length protein, corresponding to amino acids 1-341 of Human GNB3
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Reacts with
(species key)
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Hu
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Tested applications
(see key)
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ICC/IF, WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
ICC/IF: Use at a concentration of 10 µg/ml.
WB: Use at a concentration of 1 - 5 µg/ml. Predicted molecular weight: 37 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cell Membrane and Cytoplasmic
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Research areas
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Cancer >> Cancer Metabolism >> Metabolic signaling pathway >> Integration of energy metabolism
Cardiovascular >> Blood >> Blood Pressure regulation
Neuroscience >> Sensory System >> Taste system
Signal Transduction >> Signaling Pathway >> G Protein Signaling >> Heterotrimeric G Proteins >> G Proteins
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Relevance
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G proteins are composed of 3 units, alpha, beta and gamma and are involved in the modulation and transduction of various transmembrane signalling systems. There are families of related genes for each subunit. GNB3 encodes a beta subunit. Beta subunits are required for GTPase activity, for replacement of GDP by GTP, regulate alpha subunits and for G protein-effector interactions. A single-nucleotide polymorphism (C825T) in this gene is associated with essential hypertension and obesity and is also associated with the occurrence of the splice variant GNB3-s, which appears to have increased activity.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GNB3 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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GNB3 antibody images:
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 Western blot - GNB3 antibody (ab55121)
Predicted band size : 37 kDa
GNB3 antibody (ab55121) at 1ug/lane + HepG2 cell lysate at 25ug/lane.
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Immunocytochemistry/ Immunofluorescence-GNB3 antibody(ab55121)
ab55121 at 10 ug/ml staining GNB3 in human HepG2 cells by Immunocytochemistry/ Immunofluorescence.
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Search PubMed (MEDLINE) for references to GNB3
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GNB3 antibody - more information
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Customer reviews (feedback) regarding GNB3 antibody |
Customer FAQs regarding GNB3 antibody |
Protocols for GNB3 antibody |
Price and availability of products related to GNB3 antibody |
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GNB3 antibody - other tools:
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Contact Abcam with a Technical Enquiry about GNB3 antibody |
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