Anti-GPCR GPR124 antibody (ab26826)

Overview

• Product nameAnti-GPCR GPR124 antibodySee all GPCR GPR124 primary antibodies ...
• Description
  Rabbit polyclonal to GPCR GPR124
• Tested applicationsELISA more details
• Species reactivity
  Reacts with: Human
  
• Immunogen

  Synthetic peptide located in the hormone receptor domain of human GPR124.

Properties

• FormLiquid
• Storage instructionsStore at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze / thaw cycles.
• Storage bufferPreservative: None
  Constituents: PBS
• Concentration information loading...
• PurityImmunogen affinity purified
• Purification notesThis antibody was peptide affinity purified.
• Clonality Polyclonal
• IsotypeIgG
• Research Areas
  • Cancer
  • Signal transduction
  • G protein signaling
  • GPCR

  • Cancer
  • Invasion/microenvironment
  • Angiogenesis
  • Other

  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • GPCR

  • Tags & Cell Markers
  • Cell Type Markers
  • Tumor Associated

Applications

Target

• FunctionEndothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.
• Tissue specificityExpressed in endothelial cells (at protein level). Abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon.
• Sequence similaritiesBelongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.
  Contains 1 GPS domain.
  Contains 1 Ig-like (immunoglobulin-like) domain.
  Contains 4 LRR (leucine-rich) repeats.
  Contains 1 LRRCT domain.
  Contains 1 LRRNT domain.
• DomainBinds to DLG1 through its PDZ-binding motif.
• Cellular localizationCell membrane.

Target information above from: UniProt accession Q96PE1 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt
• Database links
  • Entrez Gene: 25960 Human
  • Omim: 606823 Human
  • SwissProt: Q96PE1 Human
  • Unigene: 274136 Human

• Alternative names
  DKFZp434C211 antibodyDKFZp434J0911 antibodyFLJ14390 antibody

  G protein coupled receptor 124 antibodyG-protein coupled receptor 124 antibodyGP124_HUMAN antibodyGPR 124 antibodyGPR124 antibodyKIAA1531 antibodyTEM 5 antibodyTEM5 antibodyTumor endothelial marker 5 antibodyTumor endothelial marker 5 precursor antibody

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