Anti-GPCR GPR34 antibody (ab169455)
Key features and details
- Mouse polyclonal to GPCR GPR34
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
Overview
-
Product name
Anti-GPCR GPR34 antibody
See all GPCR GPR34 primary antibodies -
Description
Mouse polyclonal to GPCR GPR34 -
Host species
Mouse -
Tested applications
Suitable for: WB, ICC/IFmore details -
Species reactivity
Reacts with: Human
Predicted to work with: Mouse, Chimpanzee, Gorilla -
Immunogen
Recombinant full length protein within Human GPCR GPR34 aa 1-400. The exact immunogen sequence used to generate this antibody is proprietary information. If additional detail on the immunogen is needed to determine the suitability of the antibody for your needs, please contact our Scientific Support team to discuss your requirements.
-
Positive control
- GPCR GPR34 transfected 293T cell lysate; 293 cells.
-
General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
Storage buffer
pH: 7.4
Constituent: 99% PBS -
Concentration information loading...
-
Purity
Protein A purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab169455 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa.
|
|
ICC/IF |
Use a concentration of 1 µg/ml.
|
Notes |
---|
WB
Use a concentration of 1 µg/ml. Predicted molecular weight: 44 kDa. |
ICC/IF
Use a concentration of 1 µg/ml. |
Target
-
Relevance
G protein-coupled receptors (GPCRs, or GPRs) contain 7 transmembrane domains and transduce extracellular signals through heterotrimeric G proteins. GPCR GPR34 is a member of this family (subfamily Orphan-A). It has been reported to be expressed in the brain, particularly in caudate, frontal cortex, putamen, and thalamus, as well as in eye, liver, and testis. ESTs have been isolated from adipose, B-cell/lung/testis, eye, liver/spleen, placenta, tonsil, and uterus libraries. -
Cellular localization
Cell membrane; Multi-pass membrane protein. -
Database links
- Entrez Gene: 473572 Chimpanzee
- Entrez Gene: 2857 Human
- Entrez Gene: 23890 Mouse
- Omim: 300241 Human
- SwissProt: P60019 Chimpanzee
- SwissProt: Q6XCF2 Gorilla
- SwissProt: Q9UPC5 Human
- SwissProt: Q9R1K6 Mouse
-
Alternative names
- G protein coupled receptor 34 antibody
- GPCR 34 antibody
- GPCR34 antibody
see all
Images
-
All lanes : Anti-GPCR GPR34 antibody (ab169455) at 1 µg/ml
Lane 1 : GPCR GPR34 transfected 293T cell lysate
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
Developed using the ECL technique.
Predicted band size: 44 kDa -
Immunofluorescent analysis of permeabilized 293 cells labeling GPCR GPR3 with ab169455 at 1µg/ml.
Protocols
Datasheets and documents
-
Datasheet download
References (1)
ab169455 has been referenced in 1 publication.
- Pan RY et al. Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-ß clearance. Sci Adv 5:eaau6328 (2019). PubMed: 30820451