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Product Name
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GRB10 antibody
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See all GRB10 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Goat polyclonal to GRB10
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Immunogen
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Synthetic peptide: KLKHHCIRVAL, corresponding to C terminal amino acids 584-594 of Human GRB 10 isoform a.
BLAST 'KLKHHCIRVAL' with  or 
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Reacts with
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Hu
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Predicted to react
(species key)
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Ms, Chk
(Due to sequence homology)
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Tested applications
(see key)
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at an assay dependent dilution. Predicted molecular weight: 67 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic, Plasma membrane
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Research areas
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Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Signal Transduction >> Adapters >> Cytoplasmic
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Relevance
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GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Goat
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Clonality
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Polyclonal
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Isotype
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IgG
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Purity
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IgG fraction
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Storage buffer
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Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline Material safety datasheet (MSDS) for this product:
Sodium Azide MSDS
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Form
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Liquid
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Concentration
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0.500 mg/ml
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Storage instructions
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Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GRB10 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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Search PubMed (MEDLINE) for references to GRB10
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GRB10 antibody - more information
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Customer reviews (feedback) regarding GRB10 antibody |
Customer FAQs regarding GRB10 antibody |
Protocols for GRB10 antibody |
Price and availability of products related to GRB10 antibody |
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GRB10 antibody - related products:
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GRB10 antibody - other tools:
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Contact Abcam with a Technical Enquiry about GRB10 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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