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Western blot - GRB10 antibody (ab55153)
(enlarge)
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Product Name
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GRB10 antibody
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See all GRB10 antibodies (4)...
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Product type
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Primary antibodies
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Description
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Mouse monoclonal to GRB10
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Immunogen
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Recombinant fragment: AVRRLQEEDQ QFRTSSLPAI PNPFPELCGP GSPPVLTPGS LPPSQAAAKQ DVKVFSEDGT SKVVEILADM TARDLCQLLV YKSHCVDDNS , corresponding to amino acids 61-151 of Human GRB 10
BLAST 'AVRRLQEEDQ QFRTSSLPAI PNPFPELCGP GSPPVLTPGS LPPSQAAAKQ DVKVFSEDGT SKVVEILADM TARDLCQLLV YKSHCVDDNS ' with  or 
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Reacts with
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RecFrag
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Predicted to react
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Hu
(Due to sequence homology)
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Tested applications
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WB
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Abreviews
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Application notes
(see key)
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Recommended dilutions
WB: Use at a concentration of 1-5 µg/ml.
This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
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Cellular localization
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Cytoplasmic, Plasma membrane
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Research areas
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Signal Transduction >> Growth Factors/Hormones >> Insulin / Insulin-like
Signal Transduction >> Adapters >> Cytoplasmic
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Relevance
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GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
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Database links
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The links below go to external sites and will open in a new browser window |
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Raised in
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Mouse
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Clonality
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Monoclonal
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Isotype
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IgG2a
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Light chain type
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kappa
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Purity
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Protein G purified
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Storage buffer
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Preservative: None
PBS, pH 7.2
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Form
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Liquid
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Concentration
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1.000 mg/ml
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Storage instructions
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Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
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At Abcam, we have one centralized database to hold all of our product information, so that everything we know about this GRB10 antibody is on this datasheet. But please do contact us if you would like any reassurance! |
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See below for GRB10 antibody images, references, products related to ab55153 and other tools.
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GRB10 antibody images:
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 Western blot - GRB10 antibody (ab55153)
Western blot against tagged recombinant protein immunogen using ab55153 GRB 10 antibody at 1ug/ml. Predicted band size of immunogen is 36 kDa. This antibody has only been tested in WB against the recombinant fragment used as immunogen. We have no data on the detection of endogenous protein.
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Search PubMed (MEDLINE) for references to GRB10
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GRB10 antibody - more information
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Customer reviews (feedback) regarding GRB10 antibody |
Customer FAQs regarding GRB10 antibody |
Protocols for GRB10 antibody |
Price and availability of products related to GRB10 antibody |
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GRB10 antibody - related products:
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GRB10 antibody - other tools:
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Contact Abcam with a Technical Enquiry about GRB10 antibody |
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All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"
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